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[勒米尔综合征变异型:具核梭杆菌败血症导致肝脓肿和肝静脉血栓形成]

[Lemierre syndrome variant: Hepatic abscesses and hepatic venous thrombosis due to Fusobacterium nucleatum septicemia].

作者信息

Le Roux K, Sève P, Gomard E, Boibieux A, Beziat C, Stankovic K, Broussolle C

机构信息

Service de médecine interne, Hôtel-Dieu, 1, place de l'hôpital, 69288 Lyon cedex 02, France.

出版信息

Rev Med Interne. 2006 Jun;27(6):482-6. doi: 10.1016/j.revmed.2005.12.013. Epub 2006 Jan 18.

Abstract

INTRODUCTION

Like Fusobacterium necrophorum, Fusobacterium nucleatum is capable causing Lemierre's syndrome. Various locations of venous thrombosis have been described associated with Fusobacterium sp. septicemia.

EXEGESIS

We describe a 43-year old alcoholic patient with F.nucleatum septicemia complicated with hepatic abscesses, middle hepatic venous thrombosis, osteomyelitis and infiltrative pneumonia. A pancreatic prosthesis was the only potentially identified infectious entrance.

CONCLUSION

Our patient showed an alternative presentation of Lemierre's syndrome, a "digestive variant". To the best of our knowledge, this is the first report of Fusobacterium septicemia associated with hepatic venous thrombosis. This report is close to the cases of portal thrombosis and opens the clinical sphere of the lemierre's syndrome, whose incidence is increasing.

摘要

引言

与坏死梭杆菌一样,具核梭杆菌也能够引发勒米尔综合征。已描述了与梭杆菌属败血症相关的静脉血栓形成的不同部位。

注释

我们描述了一名43岁的酗酒患者,其患有具核梭杆菌败血症,并伴有肝脓肿、肝中静脉血栓形成、骨髓炎和浸润性肺炎。胰体部假体是唯一可能确定的感染入口。

结论

我们的患者表现出勒米尔综合征的一种替代形式,即“消化型变体”。据我们所知,这是首例与肝静脉血栓形成相关的梭杆菌败血症报告。本报告与门静脉血栓形成病例相似,并拓宽了发病率正在上升的勒米尔综合征的临床范畴。

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