Wang S L, Zhang C S, Peng H Q, Wu K H
Department of Obstetrics and Gynecology, West China University of Medical Sciences, Chengdu.
Chin Med J (Engl). 1991 Feb;104(2):156-60.
From 1948 to 1985, a total of 630 cases of choriocarcinoma and invasive mole were treated in our hospital. The methods of treatment varied in different periods of time. In the third period (1972-1985), 5 Fu and/or KSM were the main therapeutic agents used in the treatment of 110 cases of choriocarcinoma and 99 cases of invasive mole. Metastases were observed in more than 90% of cases of choriocarcinoma and nearly 1/4 belonged to stage IV. The mortality of choriocarcinoma decreased from 84.3% to 32.7% after treatment and that of invasive mole from 32.4% to 8.1%. 43 of 80 patients treated with chemotherapy alone conceived after recovery, resulting in a total of 50 pregnancies including 31 term deliveries by 28 women. All the children are normal and healthy, the eldest being 11 years old now.
1948年至1985年，我院共收治绒毛膜癌和侵蚀性葡萄胎630例。不同时期治疗方法有所不同。第三阶段（1972 - 1985年），5-氟尿嘧啶和/或更生霉素是治疗110例绒毛膜癌和99例侵蚀性葡萄胎的主要治疗药物。绒毛膜癌90%以上病例有转移，近1/4属于IV期。绒毛膜癌治疗后死亡率从84.3%降至32.7%，侵蚀性葡萄胎死亡率从32.4%降至8.1%。80例单纯化疗患者中43例康复后受孕，共妊娠50次，其中28名妇女足月分娩31次。所有孩子均正常健康，最大的孩子现在11岁。
