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姜黄素在肺癌中的预防作用

[Preventive role of curcumin in lung cancer].

作者信息

Balcerek Maciej, Matławska Irena

机构信息

Katedra i Zakład Farmakognozji Collegium Medicum Uniwersytetu Mikołaja Kopernika w Bydgoszczy.

出版信息

Przegl Lek. 2005;62(10):1180-1.

Abstract

Carcinogens from cigarette smoke form the link between nicotine addiction and lung cancer, which is the leading cause of cancer-related mortality in the world. One of the most frequently studied chemopreventive agents is a curcumin, a natural compound extracted from turmeric that inhibits cell proliferation and induces apoptosis in human leukaemia, prostate cancer, and non-small cell lung cancer. Curcumin (diferuoylmethane) is a major yellow pigment in turmeric (Curcuma longa) and is widely used as a spice. Curcumin exhibits a variety of pharmacological effects, and has been reported to have anti-inflammatory and anti-tumor activities.

摘要

香烟烟雾中的致癌物质构成了尼古丁成瘾与肺癌之间的联系,肺癌是全球癌症相关死亡的主要原因。姜黄素是最常被研究的化学预防剂之一,它是从姜黄中提取的一种天然化合物,可抑制细胞增殖并诱导人白血病、前列腺癌和非小细胞肺癌细胞凋亡。姜黄素(二阿魏酰甲烷)是姜黄(Curcuma longa)中的主要黄色色素,被广泛用作香料。姜黄素具有多种药理作用,据报道具有抗炎和抗肿瘤活性。

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