Mikaeloff P, Biron A, Amouroux C
Ann Anesthesiol Fr. 1976;17(12):1391-7.
During 4 years (1970-1974), the numerous pre, per and post-operative datas collected for each adult operated under E.C.C. by the same surgeon, have been analysed on computer (547 cases). The myocardic protection method was unvariable: steady hypothermia of 30 degrees C, induced ventricular fibrillation, myocardic anoxia time less than 15 mn, strict out-bubbles of the left cavities. A direct perfusion of the coronary arteries has been used in case of aortotomy. Analysis of the early post-operative mortality causes and of the various post-operative myocardic complications did not reveal any baneful influence of this myocardic protection method. The average post-operative left auricular pressure, the most reliable test of the left ventricular dynamics, or its post-operative variations are independent of the ventricular fibrillation time, the perfusion time or the coronal output used.
在4年(1970 - 1974年)期间,由同一位外科医生为每位在体外循环下接受手术的成年人收集的大量术前、术中及术后数据,已通过计算机进行分析(547例)。心肌保护方法不变:30摄氏度的稳定低温、诱发心室颤动、心肌缺氧时间少于15分钟、严格排除左心腔气泡。在进行主动脉切开术时采用了冠状动脉直接灌注。对术后早期死亡原因及各种术后心肌并发症的分析未发现这种心肌保护方法有任何有害影响。术后平均左心房压力是左心室动力学最可靠的指标,其术后变化与心室颤动时间、灌注时间或冠状动脉输出量无关。