颊黏膜鳞状细胞癌患者的治疗结果。

Treatment results of patients with a squamous cell carcinoma of the buccal mucosa.

作者信息

Coppen Casper, de Wilde Peter C M, Pop Lucas A, van den Hoogen Franciscus J A, Merkx Matthias A W

机构信息

Radboud University Nijmegen Medical Centre, Department of Oral and Maxillofacial Surgery, 590, P.O. Box 9101, NL 6500, HB Nijmegen, Netherlands.

出版信息

Oral Oncol. 2006 Sep;42(8):795-9. doi: 10.1016/j.oraloncology.2005.11.017. Epub 2006 Mar 10.

DOI:10.1016/j.oraloncology.2005.11.017

PMID:16529979

Abstract

The purpose of this study was to evaluate outcome and value of follow-up of squamous cell carcinoma (SCC) of the buccal mucosa in patients treated at the Radboud University Nijmegen Medical Centre, The Netherlands. A longitudinal cohort study was performed involving 32 patients treated with curative intent (surgery on indication followed by radiotherapy) for SCC of the buccal mucosa from 1987 to 2002, with a minimum follow-up of three years. The prognosis of SCC of the buccal mucosa is comparable to other sites of the oral cavity. The success rate of therapy for a local and/or regional recurrence is very limited. Patients with a second primary tumour (SPT) can be cured if the tumour is detected in an early stage. Routine follow-up used to detect local recurrence or SPT has almost no value after five years and seems of limited value after three years.

摘要

本研究的目的是评估在荷兰奈梅亨拉德堡德大学医学中心接受治疗的颊黏膜鳞状细胞癌（SCC）患者的随访结果和价值。进行了一项纵向队列研究，纳入了1987年至2002年期间32例接受根治性治疗（根据指征进行手术，随后进行放疗）的颊黏膜SCC患者，最短随访时间为三年。颊黏膜SCC的预后与口腔其他部位相当。局部和/或区域复发的治疗成功率非常有限。如果在早期发现第二原发性肿瘤（SPT），患者可以治愈。用于检测局部复发或SPT的常规随访在五年后几乎没有价值，在三年后似乎价值有限。