Nikkola Eeva, Läärä Arja, Hinkka Susanna, Ekblad Ulla, Kero Pentti, Salonen Markku
Department of Anesthesiology, Turku University Hospital, Turku, Finland.
Acta Obstet Gynecol Scand. 2006;85(2):188-94. doi: 10.1080/00016340500409935.
We investigated whether patient-controlled epidural analgesia in labor with bupivacaine and fentanyl provides more satisfaction to mothers than intermittent bolus epidural analgesia or patient-controlled epidural analgesia with plain bupivacaine.
Ninety mothers with term, uncomplicated pregnancies were randomized to receive intermittent bolus epidural analgesia (bupivacaine + fentanyl), patient-controlled epidural analgesia (bupivacaine + fentanyl), or patient-controlled epidural analgesia (bupivacaine). Pain during labor was evaluated with a visual analog scale. Obstetric and neonatal outcomes were recorded. After delivery, the mothers were given a questionnaire covering the following themes: experience of labor pain, feeling of control, fears and expectations associated with pregnancy/with delivery/with becoming a mother, as well as pain, physical condition and emotions after delivery. To elaborate on these answers, 30 mothers were further randomized to a semistructured interview, in which the same topics were discussed. The main outcome measure was maternal satisfaction.
The intermittent bolus epidural analgesia group felt they could influence labor most (p = 0.03), and in the interview they expressed most satisfaction. In this group, the total drug utilization was smallest (bupivacaine: p <0.0001 comparing all groups, fentanyl: p = 0.03 comparing the two fentanyl-receiving groups). No differences in pain occurred. Vomiting (p = 0.04) and pruritus (p <0.0001) were more common or more severe in the groups receiving fentanyl.
We found no advantages for patient-controlled epidural analgesia over intermittent bolus epidural analgesia in terms of maternal satisfaction.
我们研究了分娩时使用布比卡因和芬太尼的患者自控硬膜外镇痛是否比间歇性推注硬膜外镇痛或单纯布比卡因患者自控硬膜外镇痛能给母亲带来更高的满意度。
90名足月、无并发症妊娠的母亲被随机分为接受间歇性推注硬膜外镇痛(布比卡因+芬太尼)、患者自控硬膜外镇痛(布比卡因+芬太尼)或患者自控硬膜外镇痛(布比卡因)。分娩时的疼痛用视觉模拟评分法进行评估。记录产科和新生儿结局。分娩后,给母亲们发放一份问卷,涵盖以下主题:分娩疼痛体验、控制感、与怀孕/分娩/成为母亲相关的恐惧和期望,以及分娩后的疼痛、身体状况和情绪。为详细阐述这些答案,30名母亲被进一步随机分为接受半结构式访谈,讨论相同主题。主要结局指标是母亲的满意度。
间歇性推注硬膜外镇痛组感觉她们对分娩的影响最大(p = 0.03),且在访谈中她们表达的满意度最高。该组的总药物用量最小(布比卡因:所有组比较p <0.0001,芬太尼:两个接受芬太尼组比较p = 0.03)。疼痛方面无差异。接受芬太尼的组中呕吐(p = 0.04)和瘙痒(p <0.0001)更常见或更严重。
就母亲满意度而言,我们发现患者自控硬膜外镇痛并不优于间歇性推注硬膜外镇痛。