Brunon A M, Setiey A, Courjon J
Ann Anesthesiol Fr. 1977;18(1):111-7.
From October 1st 1970 to October 1st 1975, electrical and clinical post-operative observation of 1.700 operations under E.C.C. allowed record of E.E.G. and thus study incidents depending of cerebral embolism during their formation. 18 cases have been seen during E.C.C. and 2 at the stop of E.C.C. In 9 cases, it was an air embolus, in 4 others an atheromatous embolus. In the 7 remaining cases, origin of the embolus is uncertain, but probably gaseous. Semiology of the accident is first only E.E.G. In 10 cases, signs were minor, and moderate in 10 others, preceding a late but hard clinical symptomatology, frequently characterized by a delayed advent of epilepsy crisis. Later on, an annoying evolution of the accident was seen in 4 cases (1 death, 3 lasting neurologic deficiency). For the treatment, many observations confirm the highly beneficient part of early hyperbaric oxygen.
从1970年10月1日至1975年10月1日，在体外循环（E.C.C.）下对1700例手术进行了术后电气及临床观察，得以记录脑电图（E.E.G.），从而研究脑栓塞形成过程中的相关事件。在体外循环期间发现了18例，在体外循环停止时发现了2例。其中9例为空气栓塞，另外4例为动脉粥样硬化栓塞。其余7例栓塞的来源不确定，但可能是气体栓塞。该意外事件的症状学最初仅表现为脑电图异常。10例症状较轻，另外10例症状中等，随后出现较晚但严重的临床症状，常以癫痫发作延迟出现为特征。后来，4例出现了不良的病情发展（1例死亡，3例遗留神经功能缺陷）。在治疗方面，许多观察结果证实了早期高压氧的显著益处。
