Conner Kenneth R, Hesselbrock Victor M, Schuckit Marc A, Hirsch Jameson K, Knox Kerry L, Meldrum Sean, Bucholz Kathleen K, Kramer John, Kuperman Samuel, Preuss Ulrich, Soyka Michael
Center for the Study and Prevention of Suicide and Department of Psychiatry, University of Rochester Medical Center, Rochester, New York 14620, USA.
J Stud Alcohol. 2006 Jan;67(1):95-101. doi: 10.15288/jsa.2006.67.95.
Alcohol dependence confers risk for suicidal behavior. Some suicide attempts are precontemplated, whereas other attempts are impulsive. The purpose of this study was to compare characteristics and correlates of impulsive and precontemplated suicide attempts.
Data were derived from analysis of The Collaborative Study on the Genetics of Alcoholism (COGA), which is a six-site family pedigree study of individuals in treatment for alcoholism (probands), relatives of probands, and control families. Subjects in the analysis were age 18 years or older with a diagnosis of current alcohol dependence according to the Diagnostic and Statistical Manual, Third Edition, Revised. Individuals reporting a lifetime history of one or more suicide attempts were divided into two strata: suicide attempters with a history of suicidal ideation that persisted for a week or more, conceptualized as attempters showing precontemplation (n=330), and suicide attempters without a history of persistent ideation, conceptualized as impulsive attempters (n=343). These groups were compared with subjects with no history of attempts (nonattempters; n=3115).
Precontemplated acts were carried out with greater intent and were more likely to result in medical treatment. Dependence on illicit drugs and history of depression were more likely among attempters showing precontemplation. Impulsive attempts were more likely to be carried out by women and individuals with higher levels of alcohol-related aggression.
Prevention of precontemplated suicide attempts by individuals with alcohol dependence should include a focus on recognition and treatment of depressive syndromes. Alcohol-related aggression was elevated among impulsive suicide attempters. Prevention efforts may include interventions targeting aggression.
酒精依赖会增加自杀行为的风险。有些自杀企图是经过预先考虑的,而其他企图则是冲动性的。本研究的目的是比较冲动性和预先考虑的自杀企图的特征及相关因素。
数据来源于对酒精中毒遗传学合作研究(COGA)的分析,这是一项针对酒精中毒治疗个体(先证者)、先证者亲属及对照家庭的六地点家系研究。分析中的受试者年龄在18岁及以上,根据《诊断与统计手册》第三版修订本诊断为当前酒精依赖。报告有过一次或多次自杀企图终生史的个体被分为两层:有持续一周或更长时间自杀意念史的自杀企图者,被概念化为有预先考虑的企图者(n = 330),以及没有持续意念史的自杀企图者,被概念化为冲动性企图者(n = 343)。将这些组与无企图史的受试者(未企图者;n = 3115)进行比较。
有预先考虑的行为实施时意图更强,更有可能导致接受治疗。有预先考虑的企图者更有可能依赖非法药物并有抑郁史。冲动性企图更有可能由女性和酒精相关攻击性水平较高的个体实施。
预防酒精依赖个体的预先考虑的自杀企图应包括关注抑郁综合征的识别和治疗。冲动性自杀企图者的酒精相关攻击性较高。预防措施可能包括针对攻击性的干预。