T cells like a firm molecular handshake.
作者信息
Dustin Michael L, Zhu Cheng
机构信息
Program in Molecular Pathogenesis, Skirball Institute of Biomolecular Medicine, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA.
出版信息
Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4335-6. doi: 10.1073/pnas.0600899103. Epub 2006 Mar 13.
Abstract
摘要
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Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4335-6. doi: 10.1073/pnas.0600899103. Epub 2006 Mar 13.
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Catch bonds: physical models, structural bases, biological function and rheological relevance.捕获键：物理模型、结构基础、生物学功能及流变学相关性
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Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76.新生成的T细胞受体微簇通过募集Zap70和SLP-76启动并维持T细胞活化。
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