Semczuk Katarzyna, Dmeńska Hanna, Dzierzanowska Danuta, Kołodziejczyk Magdalena, Gabińska Ewa, Zareba Halina
Z Instytutu "Pomnik-Centrum Zdrowia Dziecka" Warszawa.
Pneumonol Alergol Pol. 2005;73(1):41-7.
The aim of the study was, to analyze the microorganisms cultured from materials from the airways of children with cystic fibrosis treated in the Children's Memorial Health Institute in Warsaw during 1999-2002. A total of 411 samples were tested, obtained from the airways of 58 patients with diagnosed mucoviscidosis. The age of the treated patients was within the range of 1 month and 20 years. The bacteriological tests were taken during routine visits in the Consultation and Pulmonology Clinic, which took place 3-4 times a year. The most often isolated strain was Staphylococcus aureus--48%. 17% of the isolates of Haemophilus influenzae and 13% of Pseudomonas aeruginosa were obtained. Most S. aureus, P. aeruginosa and H. infiuenzae isolates showed high susceptibility to tested antimicrobial agents. About 6% of all S. aureus isolates were resistant to methicillin (MRSA). S. aureus was occurring in all age groups with the same frequency. The rods H. influenzae were cultured more often from children under 10 years, while P. aeruginosa more often from older patients.
本研究的目的是分析1999年至2002年期间在华沙儿童纪念健康研究所接受治疗的囊性纤维化儿童气道材料中培养出的微生物。共检测了411份样本,这些样本取自58名被诊断为黏液黏稠病的患者的气道。接受治疗的患者年龄在1个月至20岁之间。细菌学检测是在每年进行3至4次的咨询与肺病门诊的常规就诊期间进行的。最常分离出的菌株是金黄色葡萄球菌——占48%。分离出的流感嗜血杆菌占17%,铜绿假单胞菌占13%。大多数金黄色葡萄球菌、铜绿假单胞菌和流感嗜血杆菌分离株对所测试的抗菌药物表现出高度敏感性。所有金黄色葡萄球菌分离株中约6%对甲氧西林耐药(耐甲氧西林金黄色葡萄球菌)。金黄色葡萄球菌在所有年龄组中出现的频率相同。流感嗜血杆菌在10岁以下儿童中培养得更为常见,而铜绿假单胞菌在年龄较大的患者中培养得更为常见。