Clarke Jonathan D, Hopkins Matthew L, Eccles Ronald
Common Cold Center, Cardiff School of Biosciences, Cardiff University, Cardiff, United Kingdom.
Am J Rhinol. 2006 Jan-Feb;20(1):20-4.
The subjective sensation of nasal obstruction is of great importance to the patient and surgeon because it is this symptom that causes the patient to present for investigation and treatment. Although there are several studies in the literature looking at the correlation (or lack of correlation) between objective and subjective measures of nasal obstruction, there is no information on the minimum objective change in obstruction measured as nasal airway resistance or flow, which can be detected by a patient. The aim of this study was to measure the minimum difference in unilateral airflow that can be reliably detected by a patient.
Sixty participants with a common cold were recruited. One hundred twenty unilateral measurements of objective and subjective nasal obstruction were obtained using the technique of posterior rhinomanometry and a 100-mm visual analog scale (VAS).
Seventy-seven percent of the participants correctly discriminated between the high- and low-flow nasal passages using the VAS. Ninety-five percent of subjects correctly discriminated on the VAS between the high- and low-flow nasal passages when the difference inflow between the nasal passages was at least 100 cm3/s.
This study provides new knowledge about the limits of subjective sensation of nasal obstruction. At a level of 100 cm3/s difference in unilateral nasal flow, 95% of subjects with acute rhinitis can correctly identify the more obstructed nasal passage when using a VAS. With smaller differences in unilateral flow, the percentage of correct responses declines rapidly toward 50% as expected by chance alone.
鼻阻塞的主观感受对患者和外科医生都非常重要,因为正是这种症状促使患者前来进行检查和治疗。尽管文献中有几项研究探讨了鼻阻塞客观测量与主观测量之间的相关性(或缺乏相关性),但对于以鼻气道阻力或流量衡量的阻塞的最小客观变化,患者能够检测到的相关信息却尚无报道。本研究的目的是测量患者能够可靠检测到的单侧气流的最小差异。
招募了60名患普通感冒的参与者。使用后鼻阻力测量技术和100毫米视觉模拟量表(VAS),对鼻阻塞进行了120次单侧的客观和主观测量。
77%的参与者使用VAS能够正确区分高流量和低流量的鼻腔。当鼻腔之间的流量差异至少为100立方厘米/秒时,95%的受试者使用VAS能够正确区分高流量和低流量的鼻腔。
本研究提供了关于鼻阻塞主观感受限度的新知识。在单侧鼻腔流量差异为100立方厘米/秒的水平上,95%的急性鼻炎患者在使用VAS时能够正确识别阻塞更严重的鼻腔。当单侧流量差异较小时,正确反应的百分比会迅速下降至仅由随机因素预期的50%。