Molthen Robert C
Medical College of Wisconsin, Marquette University and Zablocki VAMC, Milwaukee, USA.
J Am Assoc Lab Anim Sci. 2006 Jan;45(1):88-93.
The research paradigm of using large laboratory animals, in which oroendotracheal intubations are relatively easy, is shifting toward the use of small animals, such as rodents, in which oropharyngeal access is limited, the arytenoid cartilage cycles are faster, and the glottis is much smaller. The considerable growth recently seen in preclinical imaging studies is accompanied by an increased number of rats and mice requiring in vivo intubation for airway management. Tracheal access is important for ventilation, administration of inhaled anesthetics, instillation of drugs or imaging agents, and maintenance of airway patency to reduce mortality during and after operations. I fashioned a light-carrying laryngoscopic blade (laryngoscope) from readily available acrylic-polymethyl methacrylate tubing and used it to perform rapid, effective tracheal intubation in rats. The laryngoscope design and intubation techniques are presented.
使用大型实验动物的研究范式正在向使用小型动物（如啮齿动物）转变。在大型实验动物中，经口气管插管相对容易，而在小型动物中，口咽通路受限，杓状软骨运动周期更快，声门小得多。最近临床前成像研究的显著增长伴随着需要进行体内插管以进行气道管理的大鼠和小鼠数量的增加。气管通路对于通气、吸入麻醉剂给药、药物或成像剂滴注以及维持气道通畅以降低手术期间及术后死亡率至关重要。我用易于获得的丙烯酸 - 聚甲基丙烯酸甲酯管制作了一个带光源的喉镜叶片（喉镜），并使用它在大鼠中进行快速、有效的气管插管。本文介绍了喉镜设计和插管技术。
