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The role of mannose in the receptor of the monocyte locomotion inhibitory factor produced by Entamoeba histolytica.

作者信息

Kretschmer R R, Castro E M, Pacheco G, Rico G, Díaz-Guerra O, Arellano J

机构信息

Division of Immunology, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City.

出版信息

Parasitol Res. 1991;77(5):374-8. doi: 10.1007/BF00931631.

DOI:10.1007/BF00931631
PMID:1653955
Abstract

The effect of the monocyte locomotion inhibitory factor (MLIF) produced by Entamoeba histolytica is diminished, if not cancelled, when human monocytes are pre-exposed to concanavalin A or sodium periodate, respectively, but not when MLIF is pretreated with sodium periodate. When the MLIF-inhibited monocyte locomotion assays were performed in the presence of 12 different carbohydrates, only the runs containing D-mannose, 4-O-beta-galactosyl-mannoside or mannan revealed a significant reduction in the inhibitory effect. Finally, the MLIF activity was virtually absorbed out with mannan-coupled Sepharose 4B beads. This suggests that D-mannose constitutes an essential part of the receptor for MLIF on the human monocyte membrane.

摘要

相似文献

1
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Parasitol Res. 1991;77(5):374-8. doi: 10.1007/BF00931631.
2
In vitro studies on the interaction of human monocytes and the monocyte locomotion inhibitory factor produced by E. histolytica.
Arch Invest Med (Mex). 1986;17 Suppl 1:243-6.
3
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引用本文的文献

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Anti-inflammatory defense mechanisms of Entamoeba histolytica.溶组织内阿米巴的抗炎防御机制。
Inflamm Res. 2011 Feb;60(2):111-7. doi: 10.1007/s00011-010-0261-x. Epub 2010 Oct 12.
2
Cyclic nucleotide changes induced in human leukocytes by a product of axenically grown Entamoeba histolytica that inhibits human monocyte locomotion.由无菌培养的溶组织内阿米巴的一种产物诱导人白细胞中发生的环核苷酸变化,该产物可抑制人单核细胞运动。
Parasitol Res. 1995;81(2):158-62. doi: 10.1007/BF00931623.

本文引用的文献

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Surface carbohydrates and surface lectins are recognition determinants in phagocytosis.表面碳水化合物和表面凝集素是吞噬作用中的识别决定因素。
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PROTEIN-CARBOHYDRATE INTERACTION. II. INHIBITION STUDIES ON THE INTERACTION OF CONCANAVALIN A WITH POLYSACCHARIDES.蛋白质-碳水化合物相互作用。II. 伴刀豆球蛋白A与多糖相互作用的抑制研究。
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Human mononuclear leukocyte chemotaxis: a quantitative assay for humoral and cellular chemotactic factors.人单核白细胞趋化性:体液和细胞趋化因子的定量测定法。
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Protein-carbohydrate interaction. 13. The interaction of concanavalin A with alpha-mannans from a variety of microorganisms.蛋白质-碳水化合物相互作用。13. 伴刀豆球蛋白A与多种微生物来源的α-甘露聚糖的相互作用。
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