Dandona Lalit, Dandona Rakhi
Health Studies Area, Centre for Human Development, Administrative Staff College of India, Hyderabad, India.
BMC Med. 2006 Mar 16;4:6. doi: 10.1186/1741-7015-4-6.
A recent estimate by the World Health Organization (WHO) suggests that 161 million persons worldwide have visual impairment, including 37 million blind (best-corrected visual acuity less than 3/60 in the better eye) and 124 million with visual impairment less severe than blindness (best-corrected acuity less than 6/18 to 3/60 in the better eye). This estimate is quoted widely, but because it is based on definitions using best-corrected visual acuity, uncorrected refractive error as a cause of visual impairment is excluded.
We reviewed data from population-based surveys of visual impairment worldwide published 1996 onwards that included presenting visual acuity, and estimated the proportion of visual impairment caused by uncorrected refractive error in different sub-regions of the world. We then extrapolated these data to estimate the worldwide burden of visual impairment including that caused by uncorrected refractive error.
The total number of persons with visual impairment worldwide, including that due to uncorrected refractive error, was estimated as 259 million, 61% higher than the commonly quoted WHO estimate. This includes 42 million persons with blindness defined as presenting visual acuity less than 3/60 in the better eye, and 217 million persons with less severe visual impairment level defined as presenting visual acuity less than 6/18 to 3/60 in the better eye, 14% and 75% higher, respectively, than the WHO estimates based on best-corrected visual acuity. Sensitivity analysis, taking into account the uncertainty of the proportion of visual impairment caused by refractive error, revealed that the number of persons in the world with visual impairment due to uncorrected refractive error could range from 82 to 117 million.
The actual burden of visual impairment worldwide, including that caused by uncorrected refractive error, is substantially higher than the commonly quoted WHO estimate that is based on best-corrected visual acuity. We suggest that the indicative estimate of 259 million persons with visual impairment worldwide, which includes 42 million blind with visual acuity less than 3/60 in the better eye, be used for further planning of the VISION 2020 initiative instead of the often quoted 161 million estimate that includes 37 million blind.
世界卫生组织(WHO)最近的一项估计表明,全球有1.61亿人存在视力障碍,其中包括3700万人失明(较好眼的最佳矫正视力低于3/60)以及1.24亿人存在比失明程度较轻的视力障碍(较好眼的最佳矫正视力低于6/18至3/60)。这一估计被广泛引用,但由于它基于使用最佳矫正视力的定义,未矫正的屈光不正作为视力障碍的一个原因被排除在外。
我们回顾了1996年及以后发表的全球基于人群的视力障碍调查数据,这些数据包含了就诊时的视力情况,并估计了世界不同次区域中由未矫正屈光不正导致的视力障碍比例。然后我们外推这些数据以估计全球视力障碍负担,包括由未矫正屈光不正导致的负担。
全球存在视力障碍的总人数,包括因未矫正屈光不正导致的人数,估计为2.59亿,比WHO经常引用的估计数高出61%。这包括4200万人失明,定义为较好眼的就诊视力低于3/60,以及2.17亿人存在程度较轻的视力障碍,定义为较好眼的就诊视力低于6/18至3/60,分别比基于最佳矫正视力的WHO估计数高出14%和75%。考虑到屈光不正导致的视力障碍比例的不确定性进行的敏感性分析表明,全球因未矫正屈光不正而存在视力障碍的人数可能在8200万至1.17亿之间。
全球视力障碍的实际负担,包括由未矫正屈光不正导致的负担,大大高于基于最佳矫正视力的WHO经常引用的估计数。我们建议,全球2.59亿视力障碍者(包括4200万较好眼视力低于3/60的盲人)的指示性估计数,应用于“视觉2020”倡议的进一步规划,而不是经常引用的包括3700万盲人的1.61亿估计数。