Aryan Henry E, Ames Christopher P, Szandera Bartek, Nguyen Andrew D, Acosta Frank L, Taylor William R
Division of Neurosurgery, University of California, San Diego (UCSD), 200 West Arbor Drive, Suite 8893, San Diego, California 92103-8893, USA.
J Clin Neurosci. 2006 Apr;13(3):349-52. doi: 10.1016/j.jocn.2005.04.027. Epub 2006 Mar 15.
Posterior lumbar interbody fusion (PLIF) and anterior lumbar interbody fusion (ALIF) have become routine alternatives to intertransverse process fusion. The use of Coblation (ArthroCare Corporation, Sunnyvale, CA) allows for routine and reproducible removal of cartilaginous endplate down to the bony endplate. Our experience with this new technology is reviewed. The authors used Coblation to prepare endplates of 10 consecutive patients undergoing interbody fusion. The results were compared to the following 10 consecutive patients undergoing interbody fusion with endplates prepared in the standard fashion with curettes and rongeurs. The same interbody grafts and instrumentation were used in all patients. Follow-up X-rays were done at 1 week, 6 weeks, 6 months, 1 year, and then each year thereafter. The 20 patients were reviewed along with their films. In each patient the disk spaces and the ALIF/PLIF cages appeared to be fused by 6 months. There was one superficial wound infection in each group. In each of the cases in which PLIF was performed, the cages were augmented by posterior lateral graft and pedicle screw fixation. All patients in both groups reported improvement in pain and/or neurologic symptoms by 6 months. The patients were followed for 4.6 years in the Coblation group and 4.1 years in the standard group. Disk space height was measured in all patients at 6 months. In the Coblation group, average disk space height was 9.0 mm compared to 8.2 mm in the standard group (p<0.1). We feel that the maintenance of normal structures within the lumbar spine with anterior/posterior lumbar interbody fusions and non-mechanical means of preparing the endplates are advantageous. Clearly, the number of patients involved and the length of follow-up limit this study, but it serves as an early indicator that endplate preparation may play a role in graft subsidence and fusion rates. Additional study is warranted.
腰椎后路椎间融合术(PLIF)和腰椎前路椎间融合术(ALIF)已成为横突间融合术的常规替代方法。使用低温等离子消融术(ArthroCare公司,加利福尼亚州桑尼维尔)可常规且可重复地将软骨终板去除至骨终板。本文回顾了我们在这项新技术方面的经验。作者使用低温等离子消融术为10例连续接受椎间融合术的患者准备终板。将结果与接下来10例连续接受椎间融合术且使用刮匙和咬骨钳以标准方式准备终板的患者进行比较。所有患者均使用相同的椎间融合器和器械。在术后1周、6周、6个月、1年及之后每年进行随访X线检查。对这20例患者及其影像学资料进行了评估。在每例患者中,椎间融合器间隙和ALIF/PLIF融合器在6个月时似乎均已融合。每组各有1例表浅伤口感染。在每例实施PLIF的病例中,融合器均通过后外侧植骨和椎弓根螺钉固定进行加强。两组所有患者均报告在6个月时疼痛和/或神经症状有所改善。低温等离子消融术组患者随访4.6年,标准组患者随访4.1年。在6个月时对所有患者测量椎间融合器间隙高度。低温等离子消融术组平均椎间融合器间隙高度为9.0mm,而标准组为8.2mm(p<0.1)。我们认为,通过腰椎前后路椎间融合术维持腰椎内正常结构以及采用非机械方式准备终板具有优势。显然,本研究涉及的患者数量和随访时间限制了研究结果,但它可作为一个早期指标,表明终板准备可能在移植物沉降和融合率中发挥作用。有必要进行进一步研究。