Suppr超能文献

危重症患者使用的肠内营养制剂之间是否存在实际差异?

Are there any real differences between enteral feed formulations used in the critically ill?

作者信息

Bongers Thomas, Griffiths Richard D

机构信息

ICU Whiston Hospital and School of Clinical Science, University of Liverpool, Liverpool, UK.

出版信息

Curr Opin Crit Care. 2006 Apr;12(2):131-5. doi: 10.1097/01.ccx.0000216580.41933.00.

Abstract

PURPOSE OF REVIEW

We know that adequate nutritional support is essential in the treatment of critically ill patients, because it can, if applied appropriately, improve the clinical outcome. Increasing evidence seems to suggest that malnutrition itself is a predictor of poor outcome in intensive care, and significant underfeeding during intensive care stay increases the risk of bloodstream infections. The purpose of this review is to highlight recent advances in enteral nutrition in the critically ill adult patient.

RECENT FINDINGS

Recent studies suggest that tight glycaemic control is associated with improved outcome. Enteral feeding should be encouraged, using simple feeding protocols, and started early if safe to do so. Gastric residual volumes do not correlate with the risk of aspiration, and therefore should be used with caution in feeding protocols. Conflicting evidence exists for supplementation with antioxidant and immunonutrition in the critically ill. Glutamine and fish oil/borage oil should be considered for burns patients and patients with adult respiratory distress syndrome, respectively.

SUMMARY

This review offers information regarding the latest developments in nutritional support via the enteral route. Further research is needed to clarify the role of enteral supplements such as antioxidants and 'immune modulating substances'.

摘要

综述目的

我们知道充足的营养支持在危重症患者治疗中至关重要,因为若应用得当,它可改善临床结局。越来越多的证据似乎表明,营养不良本身是重症监护中预后不良的一个预测因素,而在重症监护期间严重摄入不足会增加血流感染的风险。本综述的目的是强调成年危重症患者肠内营养的最新进展。

最新发现

近期研究表明,严格控制血糖与改善预后相关。应鼓励采用简单的喂养方案进行肠内喂养,并在安全的情况下尽早开始。胃残余量与误吸风险无关,因此在喂养方案中应谨慎使用。关于危重症患者补充抗氧化剂和免疫营养存在相互矛盾的证据。对于烧伤患者和成人呼吸窘迫综合征患者,应分别考虑补充谷氨酰胺和鱼油/琉璃苣油。

总结

本综述提供了有关肠内营养支持最新进展的信息。需要进一步研究以阐明抗氧化剂和“免疫调节物质”等肠内补充剂的作用。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验