Johansen J, Petersen H, Godballe C, Loft A, Grau C
Department of Oncology, Odense University Hospital, Odense, Denmark.
Q J Nucl Med Mol Imaging. 2011 Oct;55(5):500-8.
The benefit of FDG-PET in addition to standard work-up for carcinoma of unknown primary (CUP) and metastatic neck lesions has been widely described. However, most studies have been of retrospective nature with large heterogeneities in terms of workup standards and patient selection leaving several questions to be answered regarding the real value of PET in CUP. We here present an overview of the literature with focus on the current evidence of FDG-PET in detecting a primary in CUP and discuss the rationale of PET/CT in the diagnostic armamentarium of CUP.
除了对不明原发癌（CUP）和颈部转移性病变进行标准检查外，氟代脱氧葡萄糖正电子发射断层扫描（FDG-PET）的益处已得到广泛描述。然而，大多数研究具有回顾性，在检查标准和患者选择方面存在很大异质性，关于PET在CUP中的实际价值仍有几个问题有待解答。我们在此概述文献，重点关注FDG-PET在检测CUP原发灶方面的当前证据，并讨论PET/CT在CUP诊断手段中的基本原理。
