Saadat Mostafa, Zendeh-Boodi Zahra
Department of Biology, College of Sciences, Shiraz University, Shiraz, Iran.
Ann Epidemiol. 2006 Sep;16(9):708-11. doi: 10.1016/j.annepidem.2005.12.006. Epub 2006 Mar 20.
The aim of the study is to obtain more insight into the possible association between consanguinity and the incidence of deliberate self-burning.
Data were obtained by analysis of medical records of patients hospitalized in two referral burn centers: Chormy Burn Center (Bushehr Province, south of Iran) from March 21, 1998, through March 20, 2004, and Shahid Sadoqi Center of Burns and Injuries (Yazd Province, center of Iran) from March 21, 2000, through March 20, 2004.
The incidence of suicidal burns was 6.51 and 2.32/100,000 person-years for Bushehr and Yazd Provinces, respectively. The observed sex ratio of patients in both centers indicated there was a female predominance in patients with self-inflicted burns. Using patients' home addresses, patients were sorted into 16 cities. The incidence of suicide by self-burning ranged from 0.80 (for Tabas, located in Yazd Province) to 12.60/100,000 person-years (for Dilam, located in Bushehr Province). The coefficient of inbreeding defines the probability that an individual received both alleles of a pair from an identical ancestral source. There was a significant correlation between incidences of suicidal burns and mean coefficient of inbreeding (r = 0.782, df = 14, p < 0.001).
In addition to other factors, consanguineous marriage may be a risk factor that influences the incidence of suicidal burns in a population.
本研究旨在更深入了解近亲结婚与故意自焚发生率之间可能存在的关联。
通过分析两家转诊烧伤中心住院患者的病历获取数据：1998年3月21日至2004年3月20日期间的乔尔米烧伤中心（伊朗南部布什尔省），以及2000年3月21日至2004年3月20日期间的烈士萨多基烧伤与创伤中心（伊朗中部亚兹德省）。
布什尔省和亚兹德省自焚性烧伤的发生率分别为6.51和2.32/10万人口年。两个中心观察到的患者性别比表明，自伤性烧伤患者中女性占主导。利用患者的家庭住址，将患者分为16个城市。自焚自杀的发生率从0.80（位于亚兹德省的塔巴斯）到12.60/10万人口年（位于布什尔省的迪拉姆）不等。近亲繁殖系数定义了一个个体从同一祖先来源获得一对等位基因的概率。自焚性烧伤发生率与平均近亲繁殖系数之间存在显著相关性（r = 0.782，自由度 = 14，p < 0.001）。
除其他因素外，近亲结婚可能是影响人群中自焚性烧伤发生率的一个风险因素。
