Zoetelief J, Veldkamp W J H, Thijssen M A O, Jansen J T M
Department of Radiation, Radionuclides and Reactors, Faculty of Applied Sciences, Delft University of Technology, Mekelweg 15, 2629 JB Delft, The Netherlands.
Phys Med Biol. 2006 Apr 7;51(7):1807-17. doi: 10.1088/0031-9155/51/7/012. Epub 2006 Mar 16.
The nationwide breast cancer screening programme using mammography has been in full operation in The Netherlands since 1997. There is concern that the mean glandular doses due to mammography might be differing between different regions of the country due to differences in glandularity and compressed breast thickness. To investigate regional differences, glandularity, compressed breast thickness and mean glandular dose were determined for individual breasts during screening at mammography units at four locations in The Netherlands. Differences in glandularity were observed, which could be related qualitatively to differences in age of the participants at the different locations. Mean glandular dose depends on compressed breast thickness, glandularity and technical conditions of screening. The lowest average value of the mean glandular dose was found for the unit in Amsterdam. This is most likely due to the use of the Mo/Rh anode/filter combination at this unit, in addition to the Mo/Mo combination. At the other three units, almost exclusively the Mo/Mo anode/filter combination was used. Differences in mean glandular dose averaged per unit could be related mainly to differences in tube-current exposure-time product values. Consequently, it is concluded that differences in mean glandular dose at different units are marginal.
自1997年以来，荷兰全国性的使用乳房X线摄影术的乳腺癌筛查计划一直在全面实施。有人担心，由于腺体密度和乳房压缩厚度的差异，该国不同地区因乳房X线摄影术导致的平均腺体剂量可能会有所不同。为了调查地区差异，在荷兰四个地点的乳房X线摄影单位进行筛查期间，对个体乳房的腺体密度、乳房压缩厚度和平均腺体剂量进行了测定。观察到腺体密度存在差异，这在质量上可能与不同地点参与者的年龄差异有关。平均腺体剂量取决于乳房压缩厚度、腺体密度和筛查的技术条件。在阿姆斯特丹的单位发现平均腺体剂量的最低平均值。这很可能是由于该单位除了使用钼/钼阳极/滤线器组合外，还使用了钼/铑阳极/滤线器组合。在其他三个单位，几乎只使用钼/钼阳极/滤线器组合。各单位平均腺体剂量的差异主要可能与管电流-曝光时间乘积值的差异有关。因此，得出结论，不同单位的平均腺体剂量差异很小。
