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一名免疫功能正常儿童因中间型链球菌引起的淋巴结炎并发深部颈部感染。

Deep neck infection complicating lymphadenitis caused by Streptococcus intermedius in an immunocompetent child.

作者信息

Rigante Donato, Spanu Teresa, Nanni Lorenzo, Tornesello Assunta, Sanguinetti Maurizio, D'Inzeo Tiziana, Stabile Achille, Fadda Giovanni

机构信息

Department of Pediatric Sciences, Università Cattolica Sacro Cuore, Rome, Italy.

出版信息

BMC Infect Dis. 2006 Mar 22;6:61. doi: 10.1186/1471-2334-6-61.

DOI:10.1186/1471-2334-6-61
PMID:16553945
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1435756/
Abstract

BACKGROUND

Streptococcus intermedius belongs to the Streptococcus anginosus group. It is part of the normal flora of the human mouth, but it can be etiologically associated with deep-site infections.

CASE PRESENTATION

We present a case of deep neck infection complicating Streptococcus intermedius lymphadenitis, which developed in an immunocompetent 14-year-old boy with a history of recent dental work. The infection was ultimately eradicated by a combined medical and surgical approach.

CONCLUSION

Our report suggests that combined medical and surgical therapy is essential for the complete resolution of deep infections caused by Streptococcus intermedius. Molecular biological techniques can be useful in guiding the diagnostic investigation and providing insight into the possibility of occult abscesses, which are particularly common with Streptococcus intermedius infections.

摘要

背景

中间型链球菌属于咽峡炎链球菌群。它是人类口腔正常菌群的一部分,但在病因上可与深部感染相关。

病例报告

我们报告一例中间型链球菌淋巴结炎并发深部颈部感染的病例,该病例发生在一名有近期牙科治疗史的14岁免疫功能正常男孩身上。该感染最终通过药物和手术联合治疗得以根除。

结论

我们的报告表明,药物和手术联合治疗对于完全消除由中间型链球菌引起的深部感染至关重要。分子生物学技术有助于指导诊断性检查,并深入了解隐匿性脓肿的可能性,隐匿性脓肿在中间型链球菌感染中尤为常见。

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本文引用的文献

1
Genotyping by amplified fragment length polymorphism analysis reveals persistence and recurrence of infection with Streptococcus anginosus group organisms.通过扩增片段长度多态性分析进行基因分型揭示了咽峡炎链球菌群生物体感染的持续存在和复发情况。
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Deep neck infection: a present-day complication. A retrospective review of 83 cases (1998-2001).深部颈部感染:一种当代并发症。对83例病例(1998 - 2001年)的回顾性研究
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What happened to the streptococci: overview of taxonomic and nomenclature changes.链球菌怎么了:分类学和命名法变化概述
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Rapid identification of Streptococcus intermedius by PCR with the ily gene as a species marker gene.以ily基因作为种属标记基因,通过聚合酶链反应快速鉴定中间型链球菌。
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Deep neck abscess: a retrospective review of 210 cases.颈部深部脓肿:210例回顾性研究
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Streptococcus intermedius, Streptococcus constellatus, and Streptococcus anginosus ("Streptococcus milleri group") are of different clinical importance and are not equally associated with abscess.中间型链球菌、星座链球菌和咽峡炎链球菌(“米勒链球菌组”)具有不同的临床重要性,且与脓肿的关联程度并不相同。
Clin Infect Dis. 2001 May 15;32(10):1511-5. doi: 10.1086/320163. Epub 2001 Apr 20.
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Antibiotic susceptibilities of genetically characterized Streptococcus milleri group strains.基因特征明确的米勒链球菌群菌株的抗生素敏感性
Antimicrob Agents Chemother. 2001 May;45(5):1511-4. doi: 10.1128/AAC.45.5.1511-1514.2001.
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Distribution of the intermedilysin gene among the anginosus group streptococci and correlation between intermedilysin production and deep-seated infection with Streptococcus intermedius.中间溶血素基因在咽峡炎链球菌群中的分布以及中间溶血素产生与中间型链球菌深部感染之间的相关性。
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Genotypic and phenotypic characterization of "Streptococcus milleri" group isolates from a Veterans Administration hospital population.从一家退伍军人管理局医院患者群体中分离出的米勒链球菌群菌株的基因型和表型特征
J Clin Microbiol. 1999 Nov;37(11):3681-7. doi: 10.1128/JCM.37.11.3681-3687.1999.
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Species belonging to the "Streptococcus milleri" group: antimicrobial susceptibility and comparative prevalence in significant clinical specimens.属于“米勒链球菌”组的菌种:重要临床标本中的抗菌药物敏感性及比较患病率
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