实验性小鼠柯萨奇B3型心肌炎的治疗
Treatment of experimental murine Coxsackie B3 myocarditis.
作者信息
Herzum M, Huber S A, Weller R, Grebe R, Maisch B
机构信息
Philipps University, Department of Internal Medicine-Cardiology, Marburg, Germany.
出版信息
Eur Heart J. 1991 Aug;12 Suppl D:200-2. doi: 10.1093/eurheartj/12.suppl_d.200.
Abstract
Using the murine model of coxsackievirus B3-induced myocarditis we studied the effects of various immunosuppressive agents on the course and outcome of the disease in genetically different strains of mice. The response to drug treatment varied greatly among the strains of inbred mice, which suggests different immune pathomechanisms operative in mediating myocarditis.
摘要
利用柯萨奇病毒B3诱导的心肌炎小鼠模型，我们研究了各种免疫抑制剂对不同基因品系小鼠疾病进程和结局的影响。近交系小鼠品系对药物治疗的反应差异很大，这表明在介导心肌炎过程中存在不同的免疫病理机制。
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