Department of Veterinary Pathology and Hygiene, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801.
Infect Immun. 1971 Jun;3(6):735-8. doi: 10.1128/iai.3.6.735-738.1971.
Three strains of Escherichia coli isolated from infectious processes in a calf, a dog, and a cat were examined for their capacity to produce disease or death, or both, in newborn gnotobiotic piglets. The O groups represented by these particular strains of E. coli were O4: (canine origin), O6: (feline origin), and O39: (bovine origin). All three isolates upon oral administration proved to be pathogenic. Infection with the E. coli O4: (canine) or O39: (bovine) consistently produced signs of enteric coli-bacillosis and death in all 1- and 3-day-old piglets within 24 to 48 hr. The O6: (feline) isolate, on the other hand, produced a marked polyserositis and generally required 6 to 7 days to kill a piglet. Only the respective type of E. coli used in the particular trial was recovered from the diseased piglets. These findings suggest the possible role of domestic animals and household pets in the spread of potentially pathogenic E. coli to other species.
从牛、狗和猫的感染过程中分离出的三株大肠杆菌菌株，被检测其在新生无菌小猪中产生疾病或死亡或两者兼有的能力。这些特定大肠杆菌菌株所代表的 O 群分别为 O4：（来自犬类）、O6：（来自猫类）和 O39：（来自牛类）。这三种分离株经口服给药后均被证明具有致病性。感染大肠杆菌 O4：（犬类）或 O39：（牛类）后，所有 1 日龄和 3 日龄的小猪在 24 至 48 小时内均出现肠杆菌病和死亡的症状。另一方面，O6：（猫类）分离株会引起明显的多发性浆膜炎，通常需要 6 至 7 天才能杀死一只小猪。从患病的小猪中仅回收了用于特定试验的相应类型的大肠杆菌。这些发现表明，家养动物和家庭宠物可能在潜在致病性大肠杆菌传播到其他物种方面发挥作用。
