• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

麻黄及其在运动表现中的应用:运动训练师的另一个关注点?

Ephedra and its application to sport performance: another concern for the athletic trainer?

机构信息

University of Florida, Gainesville, FL.

出版信息

J Athl Train. 2001 Oct;36(4):420-4.

PMID:16558668
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC155439/
Abstract

OBJECTIVE

The ma huang herb, otherwise known as ephedra, has gained widespread popularity as an ergogenic supplement. With the sympathomimetic alkaloid ephedrine as its primary active ingredient, ma huang is marketed to reduce fatigue; increase strength, power, and speed; decrease reaction time; and improve body composition. Although numerous side effects have been associated with the use of ma huang, its popularity in athletes continues to grow. This review provides rationale for the ergogenic claims regarding ma huang and compares and contrasts those claims with data from scientifically controlled investigations.

DATA SOURCES

MEDLINE and SPORT Discus were searched from 1970 to 2000 using the key words ma huang, ephedra, and ephedrine in combination with humans, exercise, performance, and side effects.

DATA SYNTHESIS

Ephedrine has been used alone or in combination with other drugs as an effective weight-loss agent. The weight loss has been attributed to thermogenic and lipolytic effects which, in combination with the central nervous system stimulating effects, have also resulted in its use as an ergogenic aid. Most of the scientific data, however, do not support manufacturers' ergogenic claims, and numerous side effects have been associated with ephedrine use. Thus, the safety and efficacy of ma huang as an ergogenic supplement must be questioned.

CONCLUSIONS/RECOMMENDATIONS: It appears that the risks associated with the use of ma huang far outweigh any possible ergogenic benefits. Thus, it is extremely important that athletic trainers educate athletes on these issues so they can continue to perform at an optimum level in a safe and healthy manner.

摘要

目的

麻黄草药,也被称为麻黄,作为一种有益的补充剂而广受欢迎。其主要活性成分是拟交感神经生物碱麻黄碱,麻黄被宣传为可减少疲劳;提高力量、功率和速度;减少反应时间;并改善身体成分。尽管使用麻黄会引起许多副作用,但它在运动员中的受欢迎程度仍在继续增长。本综述提供了关于麻黄有益声称的基本原理,并将这些声称与经过科学控制的调查数据进行了比较和对比。

数据来源

从 1970 年到 2000 年,使用关键词麻黄、麻黄和麻黄碱与人类、运动、表现和副作用组合,在 MEDLINE 和 SPORT Discus 上进行了搜索。

数据综合

麻黄碱单独或与其他药物联合使用作为有效的减肥剂。减肥归因于热原和脂肪分解作用,这些作用与中枢神经系统刺激作用相结合,也导致其被用作有益的辅助剂。然而,大多数科学数据并不支持制造商的有益声称,并且使用麻黄碱会引起许多副作用。因此,必须质疑麻黄作为有益补充剂的安全性和有效性。

结论/建议:似乎使用麻黄的风险远远超过任何可能的有益效果。因此,运动训练员教育运动员了解这些问题非常重要,以便他们能够以安全和健康的方式继续以最佳水平表现。

相似文献

1
Ephedra and its application to sport performance: another concern for the athletic trainer?麻黄及其在运动表现中的应用:运动训练师的另一个关注点?
J Athl Train. 2001 Oct;36(4):420-4.
2
The Safety and Efficacy of Anabolic Steroid Precursors: What is the Scientific Evidence?合成代谢类固醇前体的安全性和有效性:有哪些科学依据?
J Athl Train. 2002 Jul;37(3):300-5.
3
Ephedra in perspective--a current review.麻黄的现状综述
Phytother Res. 2003 Aug;17(7):703-12. doi: 10.1002/ptr.1337.
4
Cardiovascular toxicities of performance-enhancing substances in sports.运动中提高成绩物质的心血管毒性。
Mayo Clin Proc. 2005 Oct;80(10):1307-15. doi: 10.4065/80.10.1307.
5
Cytotoxicity assessment of Ma-huang (Ephedra) under different conditions of preparation.不同制备条件下麻黄的细胞毒性评估。
Toxicol Sci. 2000 Aug;56(2):424-30. doi: 10.1093/toxsci/56.2.424.
6
[The false positive reaction of the Triage panel drug-of-abuse by herbal drugs ma-huang (Ephedra sinica (Ephedraceae))].[麻黄(麻黄科草麻黄)导致的急诊快速检验药物滥用检测板假阳性反应]
Nihon Hoigaku Zasshi. 2001 Nov;55(3):331-8.
7
Cardiotoxicity of Ma Huang/caffeine or ephedrine/caffeine in a rodent model system.麻黄/咖啡因或麻黄碱/咖啡因在啮齿动物模型系统中的心脏毒性。
Toxicol Pathol. 2007 Aug;35(5):657-64. doi: 10.1080/01926230701459978.
8
Nutritional ergogenic aids and exercise performance.营养性促力剂与运动表现。
Nutr Res Rev. 1999 Dec;12(2):255-80. doi: 10.1079/095442299108728956.
9
Neuroprotective effect of gui zhi (ramulus cinnamomi) on ma huang- (herb ephedra-) induced toxicity in rats treated with a ma huang-gui zhi herb pair.桂枝(肉桂)对麻黄-(草药麻黄)诱导的毒性的神经保护作用,以及在使用麻黄-桂枝药对治疗的大鼠中的作用。
Evid Based Complement Alternat Med. 2015;2015:913461. doi: 10.1155/2015/913461. Epub 2015 Jan 26.
10
Position of the American Dietetic Association, Dietitians of Canada, and the American College of Sports Medicine: Nutrition and athletic performance.美国饮食协会、加拿大营养师协会和美国运动医学学院的立场:营养与运动表现
J Am Diet Assoc. 2000 Dec;100(12):1543-56. doi: 10.1016/S0002-8223(00)00428-4.

引用本文的文献

1
Efficacy and safety of ephedra-containing oral medications: a systematic review, meta-analysis, and exploratory dose-response analysis for weight reduction.含麻黄碱口服药物的疗效与安全性:一项关于减肥的系统评价、荟萃分析及探索性剂量反应分析
Front Pharmacol. 2024 Oct 30;15:1397247. doi: 10.3389/fphar.2024.1397247. eCollection 2024.
2
Application of traditional Chinese therapy in sports medicine.中医疗法在运动医学中的应用。
Sports Med Health Sci. 2021 Feb 18;3(1):11-20. doi: 10.1016/j.smhs.2021.02.006. eCollection 2021 Mar.
3
Doping in Racing Pigeons (): A Review and Actual Situation in Belgium, a Leading Country in This Field.赛鸽运动中的兴奋剂问题():综述及该领域主要国家比利时的实际情况
Vet Sci. 2022 Jan 22;9(2):42. doi: 10.3390/vetsci9020042.
4
Stroke and Athletes: A Scoping Review.脑卒中与运动员:范围综述。
Int J Environ Res Public Health. 2021 Sep 24;18(19):10047. doi: 10.3390/ijerph181910047.
5
Herbal medicine for sports: a review.用于运动的草药:综述
J Int Soc Sports Nutr. 2018 Mar 15;15:14. doi: 10.1186/s12970-018-0218-y. eCollection 2018.
6
Symptomatic first-degree atrioventricular block in a young woman after taking a fat burner supplement.一名年轻女性在服用一种脂肪燃烧补充剂后出现有症状的一度房室传导阻滞。
Int J Health Sci (Qassim). 2017 Nov-Dec;11(5):79-80.
7
Anti-obesogenic and antidiabetic effects of plants and mushrooms.植物和蘑菇的抗肥胖和抗糖尿病作用。
Nat Rev Endocrinol. 2017 Mar;13(3):149-160. doi: 10.1038/nrendo.2016.142. Epub 2016 Sep 16.
8
Anti-hypotensive treatment and endothelin blockade synergistically antagonize exercise fatigue in rats under simulated high altitude.抗低血压治疗与内皮素阻断协同拮抗模拟高原环境下大鼠的运动性疲劳。
PLoS One. 2014 Jun 24;9(6):e99309. doi: 10.1371/journal.pone.0099309. eCollection 2014.
9
Herbs in exercise and sports.运动与健身中的草本植物
J Physiol Anthropol. 2012 Mar 8;31(1):4. doi: 10.1186/1880-6805-31-4.
10
Running a risk? Sport supplement toxicity with ephedrine in an amateur marathon runner, with subsequent rhabdomyolysis.冒险?一名业余马拉松运动员因服用含麻黄碱的运动补剂而中毒,继而引发横纹肌溶解症。
BMJ Case Rep. 2011 Dec 13;2011:bcr1120115093. doi: 10.1136/bcr.11.2011.5093.

本文引用的文献

1
Reducing the dose of combined caffeine and ephedrine preserves the ergogenic effect.减少咖啡因和麻黄碱的联合剂量可保留其促力效应。
Aviat Space Environ Med. 2000 Apr;71(4):415-9.
2
Psychiatric complications of Ma-huang.麻黄的精神科并发症。
Psychosomatics. 2000 Jan-Feb;41(1):58-62. doi: 10.1016/S0033-3182(00)71174-1.
3
Hypersensitivity myocarditis associated with ephedra use.与麻黄使用相关的超敏性心肌炎。
J Toxicol Clin Toxicol. 1999;37(4):485-9. doi: 10.1081/clt-100102440.
4
Combined caffeine and ephedrine ingestion improves run times of Canadian Forces Warrior Test.同时摄入咖啡因和麻黄碱可缩短加拿大军队勇士测试的跑步时间。
Aviat Space Environ Med. 1999 Apr;70(4):325-9.
5
Acute effect of ephedrine on 24-h energy balance.麻黄碱对24小时能量平衡的急性影响。
Clin Sci (Lond). 1999 May;96(5):483-91.
6
Ephedrine-type alkaloid content of nutritional supplements containing Ephedra sinica (Ma-huang) as determined by high performance liquid chromatography.通过高效液相色谱法测定含麻黄的营养补充剂中麻黄碱类生物碱的含量。
J Pharm Sci. 1998 Dec;87(12):1547-53. doi: 10.1021/js9801844.
7
Ephedrine pharmacokinetics after the ingestion of nutritional supplements containing Ephedra sinica (ma huang).摄入含有麻黄的营养补充剂后麻黄碱的药代动力学。
Ther Drug Monit. 1998 Aug;20(4):439-45. doi: 10.1097/00007691-199808000-00015.
8
Effects of caffeine, ephedrine and their combination on time to exhaustion during high-intensity exercise.咖啡因、麻黄碱及其组合对高强度运动中力竭时间的影响。
Eur J Appl Physiol Occup Physiol. 1998 Apr;77(5):427-33. doi: 10.1007/s004210050355.
9
Sudden death of a healthy college student related to ephedrine toxicity from a ma huang-containing drink.一名健康大学生因饮用含麻黄的饮料导致麻黄碱中毒而猝死。
J Clin Psychopharmacol. 1997 Oct;17(5):437-9. doi: 10.1097/00004714-199710000-00025.
10
Do pseudoephedrine or phenylpropanolamine improve maximum oxygen uptake and time to exhaustion?伪麻黄碱或去甲麻黄碱能否提高最大摄氧量和力竭时间?
Clin J Sport Med. 1997 Jul;7(3):168-73. doi: 10.1097/00042752-199707000-00003.