Harrabi Imed, Rondeau Virginie, Dartigues Jean-François, Tessier Jean-François, Filleul Laurent
Laboratoire Santé Travail Environnement, Université Bordeaux 2, France.
Environ Res. 2006 May;101(1):89-93. doi: 10.1016/j.envres.2006.01.012. Epub 2006 Mar 23.
Given the hypothesis that particulate air pollution is associated with systolic blood pressure, the effect of daily concentrations of air pollution on blood pressure was assessed in 2612 elderly subjects in the urban area of Bordeaux, France. Blood pressure was measured by a digital monitor. Particle concentrations (PM10) were obtained from the AIRAQ association that operates a local monitoring network of the air quality. To represent the ambient urban air pollution, stations had to be sufficiently correlated (i.e., correlation >0.70) and to have sufficiently similar mean levels of pollution. Linear regression was used to model the association between concentrations of particles (PM10) and systolic blood pressure. We observed associations between the fifth lag hour and systolic blood pressure for an increase of 10 microg/m3 of PM10 (beta = -1.12, 95% confidence interval: [-1.90; -0.30]). Despite contradictory results, fine particles must be considered nowadays as a major component of atmospheric air pollution in which everything must be put into practice in terms of public health actions in order to protect the general population and particularly the elderly group.
基于颗粒物空气污染与收缩压相关的假设，在法国波尔多市区的2612名老年受试者中评估了每日空气污染浓度对血压的影响。血压通过数字监测仪测量。颗粒物浓度（PM10）来自运营当地空气质量监测网络的AIRAQ协会。为了代表城市环境空气污染，监测站必须具有足够的相关性（即相关性>0.70）且污染平均水平足够相似。使用线性回归对颗粒物（PM10）浓度与收缩压之间的关联进行建模。我们观察到，对于PM10每增加10微克/立方米，在滞后第五小时与收缩压之间存在关联（β=-1.12，95%置信区间：[-1.90；-0.30]）。尽管结果相互矛盾，但如今细颗粒物必须被视为大气空气污染的主要成分，在公共卫生行动方面必须采取一切措施以保护普通人群，尤其是老年群体。
