Beckstead Robert B, Thummel Carl S
Department of Human Genetics, Howard Hughes Medical Institute, University of Utah School of Medicine, Salt Lake City, UT 84112, USA.
Cell. 2006 Mar 24;124(6):1137-40. doi: 10.1016/j.cell.2006.03.001.
Three recent papers provide new insights into endocrinology in the worm Caenorhabditis elegans. These studies identify natural steroid ligands for the DAF-12 nuclear receptor, define a new enzyme in the hormone biosynthetic pathway, and clarify the role of endocrine signaling in adult longevity.
最近的三篇论文为秀丽隐杆线虫的内分泌学提供了新的见解。这些研究确定了DAF-12核受体的天然类固醇配体,在激素生物合成途径中定义了一种新酶,并阐明了内分泌信号在成虫寿命中的作用。