Bardouille T, Picton T W, Ross B
The Rotman Research Institute, Baycrest Centre for Geriatric Care, University of Toronto, Ont., Canada M6A 2E1.
Clin Neurophysiol. 2006 May;117(5):952-8. doi: 10.1016/j.clinph.2006.01.021. Epub 2006 Mar 27.
To evaluate the spatiotemporal characteristics of ocular and cerebral current sources during voluntary eyeblinking.
Whole-head magnetoencephalographic (MEG) recordings were acquired during voluntary blinking in eight healthy adults and analysed using synthetic aperture magnetometry (SAM).
Fronto-temporal MEG sensors showed a large slow wave lasting approximately 400 ms and a small burst of activity with frequencies above 30 Hz at the initiation of the blink. Group maps of blink-related oscillatory activity at frequencies between 1-18 Hz and 32-64 Hz showed increased activity in and around the orbits during the 400 ms following blink onset. Increased oscillatory activity occurred in occipital regions 200 ms after blink onset at frequencies between 18 and 64 Hz.
Blink-related MEG signals are recorded in the regions of the eyes and in the occipital cortex. The anterior activation is likely a combination of muscle contraction and eyelid currents. Occipital activation likely represents neural processes concerned with re-establishing the visual image after transient ocular occlusion.
The possibility of eyeblink-related fields should be considered when interpreting frontal and occipital source activities during SAM analyses.
评估自主眨眼期间眼部和脑部电流源的时空特征。
在8名健康成年人自主眨眼期间进行全脑磁脑电图（MEG）记录，并使用合成孔径磁力计（SAM）进行分析。
额颞部MEG传感器在眨眼开始时显示出一个持续约400毫秒的大慢波和一个频率高于30赫兹的小活动爆发。在眨眼开始后的400毫秒内，1-18赫兹和32-64赫兹频率范围内与眨眼相关的振荡活动的组图显示眼眶及其周围活动增加。在眨眼开始后200毫秒，枕叶区域在18至64赫兹频率范围内出现振荡活动增加。
在眼睛区域和枕叶皮质记录到与眨眼相关的MEG信号。前部激活可能是肌肉收缩和眼睑电流的组合。枕叶激活可能代表与短暂性眼部遮挡后重新建立视觉图像有关的神经过程。
在SAM分析期间解释额叶和枕叶源活动时，应考虑与眨眼相关的场的可能性。
