Gonzalez Florent, Condat Bertrand, Deltenre Pierre, Mathurin Philippe, Paris Jean-Claude, Dharancy Sébastien
Service des Maladies de l'Appareil Digestif et de la Nutrition, CHRU Lille.
Gastroenterol Clin Biol. 2006 Feb;30(2):314-6. doi: 10.1016/s0399-8320(06)73173-6.
Abdominal trauma is a classic but very rare cause of portal vein thrombosis. We report the case of a patient with portal vein thrombosis and cavernoma associated with portal hypertension. Anamnesis identified a serious thoraco-abdominal trauma related to a bicycle accident 6 months before. Biological screening identified an inherited heterozygous G20210A factor II gene mutation which supports a recent notion that portal vein thrombosis most often occurs when both local and systemic aetiological factors are combined.
腹部创伤是门静脉血栓形成的一个典型但非常罕见的原因。我们报告一例门静脉血栓形成并伴有门静脉高压相关海绵状血管瘤的患者。病史显示该患者在6个月前曾发生一起与自行车事故相关的严重胸腹创伤。实验室检查发现存在遗传性杂合子G20210A因子II基因突变，这支持了最近的一种观点，即门静脉血栓形成最常发生在局部和全身病因因素同时存在时。
