亮叶美登木根皮的抗氧化活性。

Antioxidant activity of Maytenus ilicifolia root bark.

作者信息

Vellosa J C R, Khalil N M, Formenton V A F, Ximenes V F, Fonseca L M, Furlan M, Brunetti I L, Oliveira O M M F

机构信息

Biochemistry and Technology Chemistry Department, Instituto de Química, UNESP, Araraquara-SP, Brazil.

出版信息

Fitoterapia. 2006 Apr;77(3):243-4. doi: 10.1016/j.fitote.2006.02.007. Epub 2006 Mar 6.

DOI:10.1016/j.fitote.2006.02.007

PMID:16567059

Abstract

Maytenus ilicifolia is an important plant with potential on cancer treatment and has been largely used in Brazil and other countries. We have evaluated the crude ethanolic extract of M. ilicifolia as a potential antioxidant source using an assay based on the bleaching of the radical monocation 2,2'-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS(*+)) and by HOCl scavenger capacity. Trolox and uric acid were used as positive controls. The results indicated M. ilicifolia root bark as a great source of antioxidants based on its potential as scavenger of radicals.

摘要

阔叶美登木是一种在癌症治疗方面具有潜力的重要植物，已在巴西和其他国家大量使用。我们使用基于自由基单阳离子2,2'-偶氮二（3-乙基苯并噻唑啉-6-磺酸）（ABTS(*+)）的漂白测定法和次氯酸清除能力，评估了阔叶美登木的粗乙醇提取物作为潜在抗氧化剂来源的情况。将Trolox和尿酸用作阳性对照。结果表明，基于其作为自由基清除剂的潜力，阔叶美登木的根皮是抗氧化剂的重要来源。