Ding Kuiling, Wang Zheng, Wang Xingwang, Liang Yuxue, Wang Xisheng
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, P. R. China.
Chemistry. 2006 Jul 5;12(20):5188-97. doi: 10.1002/chem.200501387.
The development of heterogeneous chiral catalysts for enantioselective reactions is highly desirable in order to overcome some drawbacks of homogeneous catalysts. Different from the conventional approaches by using various types of supports or biphasic systems for the recovery and reuse of homogeneous catalysts, a conceptually new strategy for heterogenization of homogeneous chiral catalysts, that is, a "self-supporting" approach, has been developed to use homochiral metal-organic coordination polymers generated by the self-assembly of chiral multitopic ligands with metal ions, and thus obviates the use of any support. In this concept article, the success of this "self-supporting" strategy will be exemplified in heterogeneous catalysis of asymmetric carbonyl-ene, sulfoxidation, epoxidation, and asymmetric hydrogenation reactions.
为克服均相催化剂的一些缺点，开发用于对映选择性反应的多相手性催化剂非常必要。与使用各种类型的载体或双相体系来回收和再利用均相催化剂的传统方法不同，一种概念上新的均相手性催化剂多相化策略，即“自支撑”方法，已被开发出来，该方法利用手性多齿配体与金属离子自组装生成的同手性金属有机配位聚合物，从而避免使用任何载体。在这篇概念文章中，这种“自支撑”策略在不对称羰基烯反应、亚砜氧化反应、环氧化反应和不对称氢化反应的多相催化中取得的成功将得到例证。
