新西兰牛型结核分枝杆菌持续从动物传播给人类。
Continuing Mycobacterium bovis transmission from animals to humans in New Zealand.
作者信息
Baker M G, Lopez L D, Cannon M C, De Lisle G W, Collins D M
机构信息
Institute of Environmental Science and Research Ltd (ESR), Porirua, New Zealand.
出版信息
Epidemiol Infect. 2006 Oct;134(5):1068-73. doi: 10.1017/S0950268806005930. Epub 2006 Mar 29.
New Zealand has a large reservoir of Mycobacterium bovis infection in wild and farmed animals. This study aimed to assess the extent of human infection with this organism and the potential contribution of these animal sources. Combined epidemiological and laboratory investigation of human tuberculosis cases over the period 1995-2002 showed that M. bovis accounted for 2.7% (54/1997) of laboratory-confirmed human tuberculosis cases, a rate of 0.2/100,000 population. M. bovis isolates from humans (23) were typed using restriction endonuclease analysis (REA) and compared with isolates from wild and domestic animals (2600). Fourteen (61%) of the human isolates had REA patterns that were identical to patterns for isolates from cattle, deer, possums, ferrets, pigs, and occasionally cats. These results suggest a low level of ongoing M. bovis transmission from animal reservoirs to humans in New Zealand.
新西兰的野生动物和养殖动物中存在大量牛分枝杆菌感染源。本研究旨在评估人类感染该病原体的程度以及这些动物源的潜在影响。对1995年至2002年期间人类结核病病例进行的流行病学和实验室联合调查显示，牛分枝杆菌占实验室确诊人类结核病病例的2.7%（54/1997），发病率为每10万人0.2例。使用限制性内切酶分析（REA）对从人类分离出的牛分枝杆菌菌株（23株）进行分型，并与从野生动物和家畜分离出的菌株（2600株）进行比较。14株（61%）人类分离株的REA模式与牛、鹿、负鼠、雪貂、猪以及偶尔从猫分离出的菌株模式相同。这些结果表明，在新西兰，牛分枝杆菌正从动物感染源持续向人类进行低水平传播。
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