Utaida Sugunya, Pfeltz Richard F, Jayaswal R K, Wilkinson B J
Microbiology Group, Department of Biological Sciences, 210 Julian Hall, Illinois State University, Normal, Illinois 61790-4120, USA.
Antimicrob Agents Chemother. 2006 Apr;50(4):1541-5. doi: 10.1128/AAC.50.4.1541-1545.2006.
Whole-cell autolytic activity of prototypical glycopeptide-intermediate Staphylococcus aureus (GISA) Mu50 was reduced versus that of hetero-GISA Mu3 and glycopeptide-susceptible S. aureus, consistent with other GISA strains. In contrast, autolytic activity was relatively high in Mu50 crude cell walls and autolysin extracts against purified cell walls, reflecting the complexities of autolytic activity regulation.
与异源糖肽中介金黄色葡萄球菌(GISA)Mu3和糖肽敏感金黄色葡萄球菌相比,典型糖肽中介金黄色葡萄球菌(GISA)Mu50的全细胞自溶活性降低,这与其他GISA菌株一致。相比之下,Mu50粗细胞壁和自溶素提取物对纯化细胞壁的自溶活性相对较高,这反映了自溶活性调节的复杂性。