Li Bin, Zhang Dong-Ming, Luo Yong-Ming
Jiangxi University of Traditional Chinese Medicine, Nanchang 330006, China.
Zhongguo Zhong Yao Za Zhi. 2006 Jan;31(2):133-5.
To investigate the chemical constituents from the root of Lasianthus acuminatissimus of Rubiaceae.
Normal, reverse phase silica gel, macroporous resin column and HPLC chromatography were used for isolation. Spectroscopic methods (13C-NMR, 1H-NMR, DEPT, EI-MS) were used for identification.
Six compounds were isolated and elucidated as isoscopletin(I), isoscopletin-6-O-beta-D-glucopyranoside (II), beta configuration of Mudanoside-A (Ill), asperuloside (IV), (-)-pinoresinol 4-O-beta-D-glucopyranoside (V), daucosterol (VI).
These compounds were obtained from this plant for the first time.
研究茜草科尖叶粗叶木根的化学成分。
采用常规硅胶柱、反相硅胶柱、大孔树脂柱及高效液相色谱法进行分离，用光谱方法（13C-NMR、1H-NMR、DEPT、EI-MS）进行鉴定。
分离并鉴定了6个化合物，分别为异斯皮letin（I）、异斯皮letin-6-O-β-D-吡喃葡萄糖苷（II）、Mudanoside-A的β构型（III）、asperuloside（IV）、（-）-松脂醇4-O-β-D-吡喃葡萄糖苷（V）、胡萝卜苷（VI）。
这些化合物均为首次从该植物中获得。
