Konrády András
Jávorszky Odön Kórház, Belgyógyászati Osztály és Izotóp Részleg, Vác.
Orv Hetil. 2006 Mar 12;147(10):469-72.
Essential of iodine allergy is not well-known in clinical practice and it might be combined with the adverse reactions of intravascular contrast media which contain iodine. Definition of iodine allergy should be cleared up because serum also contains iodine. One should make a difference between iodine allergy and adverse reactions of contrast media. Physiological role and occurrence of iodine in the organism was reviewed, moreover, allergic reactions caused by iodine-containing chemicals (iodine and tropomyosine allergy). The contrast medium types and their immediate and late reactions were considered together with the mechanism. According to the published data and author's own experience the iodine allergy should be considered as an iodine-protein complex allergy. The cause of adverse reactions of contrast media is the whole molecule and not the iodine content of it. No cross reaction can be observed between iodine and contrast media. Iodine allergy and contrast media reactions are entirely different phenomenons. It was referred to prevention and therapy, as well.
碘过敏的本质在临床实践中并不为人熟知，它可能与含碘血管内造影剂的不良反应相关。由于血清中也含有碘，因此应明确碘过敏的定义。必须区分碘过敏和造影剂的不良反应。本文回顾了碘在机体中的生理作用及存在形式，此外，还探讨了含碘化学物质引起的过敏反应（碘和原肌球蛋白过敏）。同时考虑了造影剂的类型及其即刻和迟发反应以及相关机制。根据已发表的数据和作者自身经验，碘过敏应被视为碘 - 蛋白质复合物过敏。造影剂不良反应的原因是整个分子，而非其碘含量。碘与造影剂之间未观察到交叉反应。碘过敏和造影剂反应是完全不同的现象。文中还提及了预防和治疗方法。
