直接门静脉血栓形成的 T2*--加权磁共振成像可视化。
Direct portal vein thrombosis visualization with t2*--weighted magnetic resonance imaging.
机构信息
1. Department of Radiology, Southwest Hospital, Third Military Medical University, 30 Gaotanyan Road, Chongqing 400038, China;
出版信息
Int J Med Sci. 2013 Sep 7;10(11):1570-4. doi: 10.7150/ijms.6681. eCollection 2013.
BACKGROUND AND PURPOSE
To investigate the feasibility of direct magnetic resonance portal vein thrombosis (PVT) visualization with T2*-weighted imaging (T2*WI) without contrast agent.
METHODS
Thirty patients with PVT were included in this study. All of them were imaged with contrast-enhanced CT (CE-CT) as well as non-contrast MRI T1, T2 and T2WI. Imaging data was independently analyzed by two experienced radiologists. T2WI of all PVT was compared slice-by-slice with each of the comparison sequences (T1WI, T2WI and CE-CT) on the following categories: the location, size, boundary, and conspicuity of thrombus and portal veins.
RESULTS
The average score of PVT visualization in T2*WI was higher than T1WI and T2WI in location, size, boundary and conspicuity (t = 7.54 - 84.16, P<0.05), and higher than CE-CT in boundary and conspicuity (t = 3.03- 6.98, P<0.05). For portal vein visualization, there was no significant score difference in left, middle and right portal veins between CE-CT and T2*WI (t = -1.76- 1.35, P>0.05).
CONCLUSIONS
Our results suggest T2*WI can characterize PVT accurately with high quality without the use of intravenous contrast agents.
背景与目的
探讨 T2*-加权成像（T2*WI）是否可在不使用造影剂的情况下直接显示磁共振门静脉血栓（PVT）。
方法
本研究纳入 30 例 PVT 患者。所有患者均行对比增强 CT（CE-CT）及非对比增强 MRI T1、T2 和 T2WI 检查。由两名经验丰富的放射科医生独立对影像数据进行分析。将所有 PVT 的 T2WI 与 T1WI、T2WI 和 CE-CT 逐一进行比较，比较内容包括血栓和门静脉的位置、大小、边界和显影程度。
结果
T2*WI 对 PVT 的显示评分在位置、大小、边界和显影程度方面均高于 T1WI 和 T2WI（t = 7.54 - 84.16，P<0.05），在边界和显影程度方面高于 CE-CT（t = 3.03- 6.98，P<0.05）。在门静脉显示方面，CE-CT 和 T2*WI 在左、中、右门静脉之间的评分无显著差异（t = -1.76- 1.35，P>0.05）。
结论
我们的结果表明，T2*WI 可在不使用静脉造影剂的情况下，准确、高质量地显示 PVT。
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