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儿童慢性炎症性脱髓鞘性多发性神经病:临床及电生理特征

Chronic inflammatory demyelinating polyneuropathy in childhood: clinical and electrophysiological features.

作者信息

Uncini A, Parano E, Lange D J, De Vivo D C, Lovelace R E

机构信息

Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York.

出版信息

Childs Nerv Syst. 1991 Aug;7(4):191-6. doi: 10.1007/BF00249394.

Abstract

Five children with chronic progressive polyneuropathy but no familial history of it showed electrophysiological evidence of demyelination with partial conduction block, temporal dispersion, and focal slowing of nerve conduction velocities in multiple nerves. These findings are indicative of an acquired demyelinating polyneuropathy that is chronic and inflammatory and differentiate this condition from most of the inherited neuropathies. It is very important to recognize this entity because of the availability of various treatments.

摘要

五名患有慢性进行性多发性神经病但无家族病史的儿童显示出脱髓鞘的电生理证据,伴有部分传导阻滞、时间离散和多条神经的神经传导速度局灶性减慢。这些发现表明这是一种后天获得性的、慢性炎症性脱髓鞘性多发性神经病,将这种疾病与大多数遗传性神经病区分开来。由于有多种治疗方法,认识到这种疾病非常重要。

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