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Mammalian models of chemically induced primary malignancies exploitable for imaging-based preclinical theragnostic research.
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Presence of p53 mutations in 3Y1-B clone 1-6: a rat cell line widely used as a normal immortalized fibroblast.
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Major urinary metabolites in hamsters and rats treated with N-nitroso(2-hydroxypropyl)(2-oxopropyl)amine.
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Establishment of a human pancreatic adenocarcinoma cell line (PSN-1) with amplifications of both c-myc and activated c-Ki-ras by a point mutation.
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Animal models of exocrine pancreatic carcinogenesis.
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KRAS codon 12 mutations occur very frequently in pancreatic adenocarcinomas.
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Structure of the c-Ki-ras gene in a rat fibrosarcoma induced by 1,8-dinitropyrene.
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DNA alkylation in the hamster induced by two pancreatic carcinogens.
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Direct sequencing analysis of exon 1 of the c-K-ras gene shows a low frequency of mutations in human pancreatic adenocarcinomas.
Oncogene. 1989 Sep;4(9):1137-40.
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High frequency of Ki-ras codon 12 mutations in pancreatic adenocarcinomas.
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Experimental pancreatic cancer.
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