Reuther Lene Ørskov, Andersen Stig Ejdrup
H:S Bispebjerg Hospital, Klinisk Farmakologisk Enhed, København NV.
Ugeskr Laeger. 2006 Mar 27;168(13):1310-4.
Patients may require both low-dose aspirin (ASA) and a nonsteroidal anti-inflammatory drug (NSAID). This raises the questions of whether NSAIDs may inhibit the cardioprotective effects of low-dose ASA; whether the cardioprotective effect of low-dose ASA can be obtained by NSAIDs: and whether the combination of low-dose ASA and NSAIDs increases the risk of adverse effects. This review attempts to answer these questions.
患者可能需要同时服用低剂量阿司匹林(ASA)和非甾体抗炎药(NSAID)。这就引发了一些问题,即NSAIDs是否会抑制低剂量ASA的心脏保护作用;低剂量ASA的心脏保护作用是否能通过NSAIDs获得;以及低剂量ASA和NSAIDs联合使用是否会增加不良反应的风险。本综述试图回答这些问题。