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掺铒钇铝石榴石激光消融足底疣并辅以红光发光二极管疗法促进愈合

Er:YAG laser ablation of plantar verrucae with red LED therapy-assisted healing.

作者信息

Trelles Mario A, Allones Ines, Mayo Esther

机构信息

Instituto Médico Vilafortuny, Antoni de Gimbernat Foundation, Cambrils, Spain.

出版信息

Photomed Laser Surg. 2006 Aug;24(4):494-8. doi: 10.1089/pho.2006.24.494.

Abstract

OBJECTIVE

The aim of this study was to evaluate Er:YAG ablation of plantar verrucae with red light-emitting diode (LED) therapy to assist healing.

BACKGROUND DATA

Successful removal of troublesome plantar verrucae still presents problems, particularly regarding complete removal and pain both postoperatively and during healing. A further problem is a high recurrence rate due to the aggressive viral dissemination associated with this kind of wart.

METHODS

Over 2 years, the author treated 121 plantar warts under local anesthesia in 58 patients with Er:YAG laser ablation followed by red LED therapy to assist wound healing. The Er:YAG laser (96 J/cm2, 2.0 J/pulse, 350 microsec pulsewidth, 2-mm collimated handpiece) is used first to ablate precisely the verrucous tissue until normal architecture is seen. Immediately after treatment, a red LED therapy system is applied (633 nm, 20 min, 96 J/cm2) to the wound and surrounding area. LED therapy at the same parameters is repeated on postoperative days 2, 6, and 10. A representative plantar verruca case is presented.

RESULTS

The Er:YAG laser precisely and cleanly ablates the plantar verrucae with clear margins into normal skin architecture, exhibiting minimal secondary thermal damage. After the first treatment session, patients are usually able to walk normally without any pain, even those who have bilateral verrucae, and no exudate is usually seen from postoperative day 2 on. By postoperative day 6, the wounds have shrunk noticeably and are filled with healthy granulation tissue, and by day 15 they are usually completely healed, with minimal scarring. At the 12-month follow-up, recurrence rates have been less than 6% (3/58 patients).

CONCLUSION

From the author's experience in 121 cases, the Er:YAG laser is ideally suited for precise and speedy ablation of plantar verrucae with minimal thermal damage to surrounding tissue, which, when coupled with visible red LED therapy, has given excellent, accelerated, and pain-free healing in these difficult-to-treat and slow-to-heal lesions with very low recurrence rates.

摘要

目的

本研究旨在评估掺铒钇铝石榴石(Er:YAG)激光消融足底疣并联合红光发光二极管(LED)治疗以促进愈合的效果。

背景资料

成功去除棘手的足底疣仍然存在问题,特别是在完全去除以及术后和愈合过程中的疼痛方面。另一个问题是由于这种疣具有侵袭性的病毒传播,导致复发率很高。

方法

在两年多的时间里,作者对58例患者的121个足底疣进行了局部麻醉下的治疗,先用Er:YAG激光(96 J/cm²,2.0 J/脉冲,350微秒脉冲宽度,2毫米准直手持探头)精确消融疣状组织,直至可见正常结构。治疗后立即对伤口及周围区域应用红光LED治疗系统(633纳米,20分钟,96 J/cm²)。术后第2天、第6天和第10天以相同参数重复进行LED治疗。展示了一个具有代表性的足底疣病例。

结果

Er:YAG激光能精确、干净地消融足底疣,边缘清晰,深入正常皮肤结构,显示出最小的继发性热损伤。第一次治疗后,患者通常能够正常行走且无疼痛,即使是双侧有疣的患者,术后第2天起通常也未见渗出物。术后第6天,伤口明显缩小,充满健康的肉芽组织,到第15天通常完全愈合,瘢痕极小。在12个月的随访中,复发率低于6%(58例患者中有3例)。

结论

根据作者对121例病例的经验,Er:YAG激光非常适合精确、快速地消融足底疣,对周围组织的热损伤最小,再结合可见红光LED治疗,在这些难以治疗且愈合缓慢的病变中实现了极佳的、加速的且无痛的愈合,复发率极低。

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