Movahed Mohammad-Reza, Ahmadi-Kashani Mastaneh, Saito Yuji
Department of Medicine, Division of Cardiology, University of California, Irvine Medical Center, CA 92868, USA.
Heart Fail Rev. 2005 Dec;10(4):263-4. doi: 10.1007/s10741-005-7539-z.
The prevalence of diastolic left ventricular (LV) dysfunction in a population presenting with a suspected diagnosis of congestive heart failure (CHF) is questionable and widely variable in the current literature. To minimize the disparity, we evaluated a large echocardiographic database to investigate the prevalence of systolic and suspected diastolic LV dysfunction in those with a suspected clinical diagnosis of CHF.
We retrospectively reviewed echocardiograms performed at our institution and evaluated the prevalence of abnormal LV systolic and diastolic function in those with a suspected clinical diagnosis of CHF. Diastolic dysfunction was defined as the presence of left atrial enlargement, left ventricular hypertrophy and reverse trans-mitral inflow ratio (E/A reversal).
Of the 636 echocardiograms with CHF as the primary diagnosis, 461 had measured LV function. Normal LV systolic function were found in 238 of the patients (48%). Isolated diastolic LV dysfunction was found in 166 patients (36%). Twelve percent of the patients with a suspected clinical diagnosis of CHF had normal LV systolic and diastolic function.
Normal LV systolic function was seen in nearly one-half of the echocardiograms with a suspected clinical diagnosis of CHF. Suspected LV diastolic dysfunction was observed in one-third of the echocardiograms with a suspected clinical diagnosis of CHF.
在疑似充血性心力衰竭(CHF)的人群中,舒张期左心室(LV)功能障碍的患病率在当前文献中存在疑问且差异很大。为尽量减少这种差异,我们评估了一个大型超声心动图数据库,以调查疑似临床诊断为CHF的患者中收缩期和疑似舒张期LV功能障碍的患病率。
我们回顾性审查了在我们机构进行的超声心动图检查,并评估了疑似临床诊断为CHF的患者中左心室收缩和舒张功能异常的患病率。舒张功能障碍定义为存在左心房扩大、左心室肥厚和二尖瓣反流比值逆转(E/A逆转)。
在以CHF为主要诊断的636份超声心动图中,461份测量了LV功能。238例患者(48%)左心室收缩功能正常。166例患者(36%)存在孤立性舒张期LV功能障碍。疑似临床诊断为CHF的患者中,12%的患者左心室收缩和舒张功能正常。
在疑似临床诊断为CHF的超声心动图中,近一半显示左心室收缩功能正常。在疑似临床诊断为CHF的超声心动图中,三分之一观察到疑似左心室舒张功能障碍。