Obara T, Maguchi H, Saitoh Y, Ura H, Koike Y, Kitazawa S, Namiki M
Third Department of Internal Medicine, Asahikawa Medical College, Japan.
Am J Gastroenterol. 1991 Nov;86(11):1619-25.
We report our experience with nine patients with "mucin-producing tumor of the pancreas," in which abundant mucin secreted by the tumor cells played a major role in the characteristic alterations of the pancreatic duct system. Four of nine patients presented with pancreatitis. Ultrasound and computed tomography demonstrated a well-defined cystic mass and dilated main pancreatic duct. Endoscopic retrograde pancreatography showed ductectatic character, i.e., diffuse dilatation of main duct and/or cystic dilatation of the branch ducts with filling defects of mucin. Ultrasound proved to be a good screening test. However, the diagnosis was confirmed on endoscopic retrograde pancreatography. Nine of our cases had no peripancreatic invasion or metastasis, resulting in a good prognosis after pancreatectomy. Mucin-producing tumor of the pancreas is a unique clinical entity that should be distinguished from "common" pancreatic carcinomas, and a favorable prognosis can be expected after surgical operation.
我们报告了9例“胰腺黏液产生性肿瘤”患者的情况，肿瘤细胞分泌的大量黏液在胰腺导管系统的特征性改变中起主要作用。9例患者中有4例表现为胰腺炎。超声和计算机断层扫描显示边界清晰的囊性肿块和主胰管扩张。内镜逆行胰胆管造影显示导管扩张特征，即主胰管弥漫性扩张和/或分支胰管囊性扩张伴黏液充盈缺损。超声被证明是一种很好的筛查方法。然而，诊断是通过内镜逆行胰胆管造影证实的。我们的9例病例均无胰周侵犯或转移，胰腺切除术后预后良好。胰腺黏液产生性肿瘤是一种独特的临床实体，应与“常见”胰腺癌相鉴别，手术治疗后有望获得良好预后。
