Department of Chemistry, Stanford University, Stanford, California 94305.
Proc Natl Acad Sci U S A. 1980 Jun;77(6):3115-9. doi: 10.1073/pnas.77.6.3115.
Using the lattice model for a liquid, we treat the packing of short-chain molecules in interphases such as bilayer membranes. The constant density in the interphase imposes intermolecular constraints on the configurations of the flexible chains. The statistical theory here presented predicts a diffuse distribution of chain ends near the bilayer midplane; no adjustable parameters are required. Inasmuch as some of the chains terminate relatively near the polar interface, the number of chains reaching deeper planar layers is diminished. Consequently, configurational freedom increases with depth. This is the source of the well-known disorder gradient.
我们使用液体的晶格模型来处理双层膜等界面中短链分子的堆积。界面中的恒定密度对柔性链的构型施加了分子间约束。这里提出的统计理论预测了链末端在双层中间平面附近的扩散分布;不需要可调参数。由于一些链相对靠近极性界面终止,到达较深平面层的链的数量减少。因此,构象自由度随深度增加。这就是众所周知的无序梯度的来源。