Friedrich Miescher-Institut, P.O. Box 2543, CH-4002 Basel, Switzerland.
Proc Natl Acad Sci U S A. 1987 Apr;84(7):1824-8. doi: 10.1073/pnas.84.7.1824.
A protein kinase has been found to be associated with particles of the plant virus cauliflower mosaic virus. This protein kinase can phosphorylate endogenous viral capsid proteins in vitro and exchange substrates with casein kinase type II. The activity is not affected by cAMP but is enhanced considerably by ADP. The cofactor is either Mn(2+) or Mg(2+), and the phosphate donor is either ATP or GTP. Serine and threonine residues are phosphorylated.
已发现一种蛋白激酶与花椰菜花叶病毒的颗粒有关。这种蛋白激酶能够在体外使内源性病毒衣壳蛋白磷酸化,并与酪蛋白激酶Ⅱ交换底物。该活性不受 cAMP 影响,但 ADP 可显著增强。辅因子为 Mn(2+)或 Mg(2+),磷酸供体为 ATP 或 GTP。丝氨酸和苏氨酸残基被磷酸化。