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A CA repeat 30-70 KB downstream from the adenomatous polyposis coli (APC) gene.

作者信息

Spirio L, Joslyn G, Nelson L, Leppert M, White R

机构信息

Department of Human Genetics, University of Utah, Salt Lake City 84112.

出版信息

Nucleic Acids Res. 1991 Nov 25;19(22):6348. doi: 10.1093/nar/19.22.6348.

DOI:10.1093/nar/19.22.6348
PMID:1659692
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC329171/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/016a/329171/14491b67d2d6/nar00102-0265-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/016a/329171/14491b67d2d6/nar00102-0265-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/016a/329171/14491b67d2d6/nar00102-0265-a.jpg

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本文引用的文献

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Identification and characterization of the familial adenomatous polyposis coli gene.
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J Clin Pathol. 2004 Oct;57(10):1084-8. doi: 10.1136/jcp.2004.018507.
4
Ki-ras gene mutations, LOH of the APC and DCC genes, and microsatellite instability in primary colorectal carcinoma are not associated with micrometastases in pericolonic lymph nodes or with patients' survival.原发性结直肠癌中的Ki-ras基因突变、APC和DCC基因的杂合性缺失以及微卫星不稳定性与结肠周淋巴结微转移或患者生存率无关。
J Clin Pathol. 2004 Sep;57(9):938-42. doi: 10.1136/jcp.2004.017814.
5
Molecular changes in the Ki-ras and APC genes in primary colorectal carcinoma and synchronous metastases compared with the findings in accompanying adenomas.原发性结直肠癌及同时性转移灶中Ki-ras和APC基因的分子变化与伴发腺瘤的研究结果比较。
Mol Pathol. 2003 Jun;56(3):137-40. doi: 10.1136/mp.56.3.137.
6
Analysis of allelic imbalance in patients with colorectal cancer according to stage and presence of synchronous liver metastases.根据分期及是否存在同时性肝转移对结直肠癌患者的等位基因不平衡进行分析。
Ann Surg. 2001 Dec;234(6):795-802; discussion 802-3. doi: 10.1097/00000658-200112000-00011.
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Familial/bilateral and sporadic testicular germ cell tumors show frequent genetic changes at loci with suggestive linkage evidence.家族性/双侧性和散发性睾丸生殖细胞肿瘤在具有提示性连锁证据的基因座上常出现基因改变。
Neoplasia. 2001 May-Jun;3(3):196-203. doi: 10.1038/sj.neo.7900153.
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Dig Dis Sci. 2000 Oct;45(10):2022-8. doi: 10.1023/a:1005560428937.
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Neoplastic progression occurs through mutator pathways in hyperplastic polyposis of the colorectum.肿瘤进展通过结直肠增生性息肉病中的突变途径发生。
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Gut. 2000 Jul;47(1):37-42. doi: 10.1136/gut.47.1.37.