使用基因分型仪进行基于参考的注释。

Chatterji Sourav, Pachter Lior

Department of Computer Science, University of California at Berkeley, Berkeley, CA 94720, USA.

Genome Biol. 2006;7(4):R29. doi: 10.1186/gb-2006-7-4-r29. Epub 2006 Apr 5.

We introduce GeneMapper, a program for transferring annotations from a well annotated genome to other genomes. Drawing on high quality curated annotations, GeneMapper enables rapid and accurate annotation of newly sequenced genomes and is suitable for both finished and draft genomes. GeneMapper uses a profile based approach for mapping genes into multiple species, improving upon the standard pairwise approach. GeneMapper is freely available for academic use.

我们推出了GeneMapper，这是一个用于将注释从注释完善的基因组转移到其他基因组的程序。借助高质量的精心策划的注释，GeneMapper能够对新测序的基因组进行快速准确的注释，适用于完成的基因组和草图基因组。GeneMapper使用基于概要文件的方法将基因映射到多个物种，对标准的成对方法进行了改进。GeneMapper可供学术使用，免费获取。