Wille S, Heidenreich A, von Knobloch R, Hofmann R, Engelmann U
Division of Gynecology and Neurourology, University of Cologne, Cologne, Germany.
Urol Int. 2006;76(3):223-6. doi: 10.1159/000091623.
The aim of this retrospective study was to evaluate various factors that may influence post-prostatectomy incontinence (PPI).
1,088 men with prostate cancer underwent radical retropubic prostatectomy. 742 patients were evaluable for analysis. Continence was defined as usage of no or one pad daily. Mean follow-up was 45 months (12-143).
Based on protective pad requirement 100% and 76% of men were continent at baseline and at the time of questionnaire evaluation (at least 12 months), respectively. Univariate analysis was performed to identify factors that may influence the return of continence. Age, body mass index (BMI), previous TUR-P, smoking, hypertension, diabetes and attempted nerve sparing did not predict postoperative continence status.
In contrast to several reports, our analysis revealed that age, BMI, previous TUR-P, smoking, hypertension and diabetes do not have a statistically significant impact on continence after radical retropubic prostatectomy and are therefore not useful as predictors for PPI.
本回顾性研究的目的是评估可能影响前列腺切除术后尿失禁(PPI)的各种因素。
1088例前列腺癌男性患者接受了根治性耻骨后前列腺切除术。742例患者可进行分析评估。尿失禁的定义为每天使用不超过一片尿垫。平均随访时间为45个月(12 - 143个月)。
根据尿垫使用需求计算,分别有100%和76%的男性在基线时及问卷调查评估时(至少12个月)能保持尿失禁。进行单因素分析以确定可能影响尿失禁恢复的因素。年龄、体重指数(BMI)、既往经尿道前列腺电切术(TUR - P)、吸烟、高血压、糖尿病以及保留神经尝试均不能预测术后尿失禁状态。
与一些报道相反,我们的分析显示年龄、BMI、既往TUR - P、吸烟、高血压和糖尿病对根治性耻骨后前列腺切除术后的尿失禁无统计学显著影响,因此不能作为PPI的预测指标。