Gan Jean C, Glazer Paul A
EBI LP, Department of Research and Development, Parsippany, NJ, USA.
Eur Spine J. 2006 Sep;15(9):1301-11. doi: 10.1007/s00586-006-0087-y. Epub 2006 Apr 8.
Electrical stimulation therapies have been used for more than 30 years to enhance spinal fusions. Although their positive effects on spinal fusions have been widely reported, the mechanisms of action of the technologies were only recently identified. Three types of technologies are available clinically: direct current, capacitive coupling, and inductive coupling. The latter is the basis of pulsed electromagnetic fields and combined magnetic fields. This review summarizes the current concepts on the mechanisms of action, animal and clinical studies, and cost justification for the use of electrical stimulation for spinal fusions. Scientific studies support the validity of electrical stimulation treatments. The mechanisms of action of each of the three electrical stimulation therapies are different. New data demonstrates that the upregulation of several growth factors may be responsible for the clinical success seen with the use of such technologies.
电刺激疗法已被用于促进脊柱融合超过30年。尽管其对脊柱融合的积极作用已被广泛报道,但这些技术的作用机制直到最近才被确定。临床上有三种类型的技术:直流电、电容耦合和电感耦合。后者是脉冲电磁场和组合磁场的基础。本综述总结了关于电刺激用于脊柱融合的作用机制、动物和临床研究以及成本合理性的当前概念。科学研究支持电刺激治疗的有效性。三种电刺激疗法各自的作用机制不同。新数据表明,几种生长因子的上调可能是使用这些技术所取得临床成功的原因。