Arkhipova N A, Troshina E M, Shabalov V A
Zh Vyssh Nerv Deiat Im I P Pavlova. 1991 Jul-Aug;41(4):655-62.
To study the role of subcortical structures and cerebellum nuclei in the genesis of the human brain potentials connected with motion patients were examined with parkinsonism and hyperkinetic form of children cerebral paralysis. In one group of patients the motor responses were recorded by means of long-term electrodes implanted with the medical purpose into the ventro-oral group of thalamus nuclei, subcortical nuclei and dentate cerebellum nuclei. In patients of the second group potentials, connected with motion were led from the scalp before and after one-moment destruction in the zone of the same structures. In ventro-oral and reticular thalamus nuclei lateral and medial segments of the pale globe and in the cerebellum dentate nucleus post-motor components were recorded which were considered as electrographic expression of motion realization and completion processes (P2 and N3) and also as slow negative oscillation (component N1), that pointed to participation of the studied structures not only in regulation of voluntary movement but also in the process of movement preparation. Absence of N2 component at recording motor responses from deep electrodes and its sufficient stability at scalp leads gave the reason to suggest that its genesis was connected with the cortex activity.
为了研究皮层下结构和小脑核在与运动相关的人脑电位发生过程中的作用,对患有帕金森病和儿童脑瘫多动型的患者进行了检查。在一组患者中,通过为医疗目的植入丘脑腹口核、皮层下核和齿状小脑核的长期电极记录运动反应。在第二组患者中,在同一结构区域进行一次性破坏前后,从头皮引出与运动相关的电位。在丘脑腹口核和网状核、苍白球的外侧和内侧段以及小脑齿状核中记录到运动后成分,这些成分被认为是运动实现和完成过程的电图表现(P2和N3),也被认为是缓慢负向振荡(成分N1),这表明所研究的结构不仅参与自主运动的调节,还参与运动准备过程。在从深部电极记录运动反应时未出现N2成分,而在头皮导联中其具有足够的稳定性,这使得有理由推测其发生与皮层活动有关。