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[人脑皮质下运动结构疾病中运动电位的特征]

[Characteristics of the motor potentials in disorders of the subcortical motor structures of the human brain].

作者信息

Troshina E M

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1989 Jan-Feb;39(1):37-43.

PMID:2735129
Abstract

Properties of motor potentials (MPs) were studied in patients with disturbance of function of subcortical motor structures--disturbance causing parkinsonism manifestations. MPs components are singled out preceding movement--"readiness potential" (N1), "motor potential" (N2) and MP components which are electrophysiological correlates of realization processes (component P2) and movement completion (component N3). It is revealed that MPs in patients with parkinsonism are changed in comparison with the norm; the most significant differences are observed in components N1, P2, N3, what is expressed in prolongation and a certain amplitude decrease of these components. Amplitude-temporal parameters most similar to the norm belong to the component N2, which is considered as an electrophysiological correlate of movement triggering. A hypothesis is suggested on its cortical origin.

摘要

对患有皮质下运动结构功能障碍(导致帕金森氏症表现的功能障碍)的患者的运动电位(MPs)特性进行了研究。在运动之前区分出MPs的组成部分——“准备电位”(N1)、“运动电位”(N2),以及作为实现过程(P2成分)和运动完成(N3成分)的电生理相关物的MPs组成部分。结果显示,与正常情况相比,帕金森氏症患者的MPs发生了变化;在N1、P2、N3成分中观察到最显著的差异,表现为这些成分的延长和一定幅度的降低。与正常情况最相似的幅度-时间参数属于N2成分,该成分被认为是运动触发的电生理相关物。提出了一个关于其皮质起源的假说。

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