Lamas Ferreiro A, López-Herce J, Sánchez Pérez L, Mencía Bartolomé S, Borrego Domínguez R, Carrillo Alvarez A
Sección de cuidados Intensivos Pediátricos, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
An Pediatr (Barc). 2006 Apr;64(4):354-9. doi: 10.1157/13086524.
Middle latency auditory evoked potentials (MLAEP) reflect changes in electroencephalogram waves after an auditory signal and represent the earliest cortical response to acoustic stimulus. They are therefore used to measure variations in the level of consciousness. MLEAP have been used to measure the depth of anesthesia during surgical procedures, but experience in critical care patients is very limited.
To analyze the utility of MLAEP for monitoring the level of sedation in critically ill children.
Level of consciousness was monitored through MLAEP by placing special headphones and three sensors situated in the frontal and preauricular regions. Simultaneously, the level of sedation was measured using the COMFORT scale and the Bispectral Index (BIS) in distinct clinical situations.
We studied six critically ill children in whom MLAEP helped us to evaluate the level of consciousness: light sedation, natural sleep, deep sedation, sedation in a paralyzed child, and brain death. MLAEP showed a good correlation with the COMFORT scale and BIS in light and deep sedation and were effective in the early detection of brain death in one patient. In the paralyzed patient, MLAEP was able to detect undersedation. In one patient, a pacemaker interfered with the MLAEP signal.
MLAEP can be useful in evaluating the level of consciousness and sedation in critically ill children. Further studies with larger samples are required to analyze the limitations and reproducibility of this type of monitoring in children of different ages.
中潜伏期听觉诱发电位(MLAEP)反映听觉信号后脑电图波的变化,代表对听觉刺激的最早皮层反应。因此,它们被用于测量意识水平的变化。MLAEP已被用于测量手术过程中的麻醉深度,但在重症监护患者中的经验非常有限。
分析MLAEP在监测危重症儿童镇静水平中的应用价值。
通过在额部和耳前区域放置特殊耳机和三个传感器,利用MLAEP监测意识水平。同时,在不同临床情况下使用舒适量表和脑电双频指数(BIS)测量镇静水平。
我们研究了六名危重症儿童,MLAEP帮助我们评估了他们的意识水平:浅镇静、自然睡眠、深镇静、瘫痪儿童的镇静以及脑死亡。MLAEP在浅镇静和深镇静状态下与舒适量表和BIS显示出良好的相关性,并且在一名患者中有效地早期检测到了脑死亡。在瘫痪患者中,MLAEP能够检测到镇静不足。在一名患者中,起搏器干扰了MLAEP信号。
MLAEP在评估危重症儿童的意识和镇静水平方面可能有用。需要进行更大样本量的进一步研究,以分析这种监测方式在不同年龄段儿童中的局限性和可重复性。