• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

危重症患儿的中潜伏期听觉诱发电位:初步研究

[Middle latency auditory evoked potentials in critical care children: preliminary study].

作者信息

Lamas Ferreiro A, López-Herce J, Sánchez Pérez L, Mencía Bartolomé S, Borrego Domínguez R, Carrillo Alvarez A

机构信息

Sección de cuidados Intensivos Pediátricos, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

出版信息

An Pediatr (Barc). 2006 Apr;64(4):354-9. doi: 10.1157/13086524.

DOI:10.1157/13086524
PMID:16606573
Abstract

BACKGROUND

Middle latency auditory evoked potentials (MLAEP) reflect changes in electroencephalogram waves after an auditory signal and represent the earliest cortical response to acoustic stimulus. They are therefore used to measure variations in the level of consciousness. MLEAP have been used to measure the depth of anesthesia during surgical procedures, but experience in critical care patients is very limited.

OBJECTIVE

To analyze the utility of MLAEP for monitoring the level of sedation in critically ill children.

METHODS

Level of consciousness was monitored through MLAEP by placing special headphones and three sensors situated in the frontal and preauricular regions. Simultaneously, the level of sedation was measured using the COMFORT scale and the Bispectral Index (BIS) in distinct clinical situations.

RESULTS

We studied six critically ill children in whom MLAEP helped us to evaluate the level of consciousness: light sedation, natural sleep, deep sedation, sedation in a paralyzed child, and brain death. MLAEP showed a good correlation with the COMFORT scale and BIS in light and deep sedation and were effective in the early detection of brain death in one patient. In the paralyzed patient, MLAEP was able to detect undersedation. In one patient, a pacemaker interfered with the MLAEP signal.

CONCLUSIONS

MLAEP can be useful in evaluating the level of consciousness and sedation in critically ill children. Further studies with larger samples are required to analyze the limitations and reproducibility of this type of monitoring in children of different ages.

摘要

背景

中潜伏期听觉诱发电位(MLAEP)反映听觉信号后脑电图波的变化,代表对听觉刺激的最早皮层反应。因此,它们被用于测量意识水平的变化。MLAEP已被用于测量手术过程中的麻醉深度,但在重症监护患者中的经验非常有限。

目的

分析MLAEP在监测危重症儿童镇静水平中的应用价值。

方法

通过在额部和耳前区域放置特殊耳机和三个传感器,利用MLAEP监测意识水平。同时,在不同临床情况下使用舒适量表和脑电双频指数(BIS)测量镇静水平。

结果

我们研究了六名危重症儿童,MLAEP帮助我们评估了他们的意识水平:浅镇静、自然睡眠、深镇静、瘫痪儿童的镇静以及脑死亡。MLAEP在浅镇静和深镇静状态下与舒适量表和BIS显示出良好的相关性,并且在一名患者中有效地早期检测到了脑死亡。在瘫痪患者中,MLAEP能够检测到镇静不足。在一名患者中,起搏器干扰了MLAEP信号。

结论

MLAEP在评估危重症儿童的意识和镇静水平方面可能有用。需要进行更大样本量的进一步研究,以分析这种监测方式在不同年龄段儿童中的局限性和可重复性。

相似文献

1
[Middle latency auditory evoked potentials in critical care children: preliminary study].危重症患儿的中潜伏期听觉诱发电位:初步研究
An Pediatr (Barc). 2006 Apr;64(4):354-9. doi: 10.1157/13086524.
2
Changes in the auditory evoked potentials and the bispectral index following propofol or propofol and alfentanil.丙泊酚或丙泊酚与阿芬太尼合用后听觉诱发电位和脑电双频指数的变化。
Anesthesiology. 2000 May;92(5):1300-10. doi: 10.1097/00000542-200005000-00018.
3
Assessing sedation in critically ill children by bispectral index, auditory-evoked potentials and clinical scales.通过脑电双频指数、听觉诱发电位和临床量表评估危重症儿童的镇静状态。
Intensive Care Med. 2008 Nov;34(11):2092-9. doi: 10.1007/s00134-008-1198-1. Epub 2008 Jul 4.
4
Bispectral index and middle latency auditory evoked potentials in children younger than two-years-old.两岁以下儿童的脑电双频指数和中潜伏期听觉诱发电位
Anesth Analg. 2008 Feb;106(2):426-32, table of contents. doi: 10.1213/ane.0b013e3181602be1.
5
Assessment of the level of sedation in children after cardiac surgery.心脏手术后儿童镇静水平的评估。
Ann Thorac Surg. 2009 Jul;88(1):144-50. doi: 10.1016/j.athoracsur.2009.03.074.
6
The performance of electroencephalogram bispectral index and auditory evoked potential index to predict loss of consciousness during propofol infusion.脑电图双谱指数和听觉诱发电位指数在预测丙泊酚输注期间意识丧失方面的表现。
Anesth Analg. 1999 Nov;89(5):1311-5.
7
[Use of the Bispectral Index in monitoring critically-ill children].[脑电双频指数在危重症儿童监测中的应用]
An Pediatr (Barc). 2006 Jan;64(1):96-9. doi: 10.1016/s1695-4033(06)70017-0.
8
Analysis of bispectral index and middle latency auditory-evoked potentials parameters in critically ill children.
J Clin Neurophysiol. 2009 Jun;26(3):150-4. doi: 10.1097/WNP.0b013e3181a184fe.
9
Brainstem auditory evoked potentials and middle latency auditory evoked potentials in young children.婴幼儿脑干听觉诱发电位和中潜伏期听觉诱发电位。
J Clin Neurosci. 2013 Mar;20(3):383-8. doi: 10.1016/j.jocn.2012.02.038. Epub 2012 Dec 21.
10
The Use of Middle Latency Auditory Evoked Potentials (MLAEP) as Methodology for Evaluating Sedation Level in Propofol-Drug Induced Sleep Endoscopy (DISE) Procedure.应用中潜伏期听觉诱发电位(MLAEP)作为评估异丙酚药物诱导睡眠内镜检查(DISE)镇静水平的方法。
Int J Environ Res Public Health. 2021 Feb 20;18(4):2070. doi: 10.3390/ijerph18042070.

引用本文的文献

1
Assessing sedation in critically ill children by bispectral index, auditory-evoked potentials and clinical scales.通过脑电双频指数、听觉诱发电位和临床量表评估危重症儿童的镇静状态。
Intensive Care Med. 2008 Nov;34(11):2092-9. doi: 10.1007/s00134-008-1198-1. Epub 2008 Jul 4.