Palencia Roberto, Gafni Amiram, Hannah Mary E, Ross Susan, Willan Andrew R, Hewson Sheila, McKay Darren, Hannah Walter, Whyte Hilary, Amankwah Kofi, Cheng Mary, Guselle Patricia, Helewa Michael, Hodnett Ellen D, Hutton Eileen K, Kung Rose, Saigal Saroj
Maternal, Infant and Reproductive Health Research Unit at the Centre for Research in Women's Health, University of Toronto, Toronto, Ont.
CMAJ. 2006 Apr 11;174(8):1109-13. doi: 10.1503/cmaj.050796.
The Term Breech Trial compared the safety of planned cesarean and planned vaginal birth for breech presentations at term. The combined outcome of perinatal or neonatal death and serious neonatal morbidity was found to be significantly lower among babies delivered by planned cesarean section. In this study we conducted a cost analysis of the 2 approaches to breech presentations at delivery.
We used a third-party-payer (i.e., Ministry of Health) perspective. We included all costs for physician services and all hospital-related costs incurred by both the mother and the infant. We collected health care utilization and outcomes for all study participants during the trial. We used only the utilization data from countries with low national rates of perinatal death (< or = 20/1000). Seven hospitals across Canada (4 teaching and 3 community centres) were selected for unit cost calculations.
The estimated mean cost of a planned cesarean was significantly lower than that of a planned vaginal birth (7165 dollars v. 8042 dollars per mother and infant; mean difference -877 dollars, 95% credible interval -1286 dollars to -473 dollars). The estimated mean cost of a planned cesarean was lower than that of a planned vaginal birth for both women having a first birth (7255 dollars v. 8440 dollars) and women having had at least one prior birth (7071 dollars v. 7559 dollars). Although the treatment effect was largest in the subgroup of women having their first child, there was no statistically significant interaction between treatment and parity since the 95% credible intervals for difference in treatment effects between parity equalling zero and parity of one or greater all include zero.
Planned cesarean section was found to be less costly than planned vaginal birth for the singleton fetus in a breech presentation at term in the Term Breech Trial.
足月臀位分娩试验比较了足月臀位分娩时计划剖宫产和计划阴道分娩的安全性。结果发现,计划剖宫产分娩的婴儿围产期或新生儿死亡及严重新生儿发病率的综合结局显著更低。在本研究中,我们对分娩时臀位的两种处理方法进行了成本分析。
我们采用第三方支付者(即卫生部)的视角。我们纳入了医师服务的所有成本以及母亲和婴儿产生的所有与医院相关的成本。我们收集了试验期间所有研究参与者的医疗保健利用情况和结局。我们仅使用围产期死亡率较低(≤20/1000)国家的利用数据。选择了加拿大的7家医院(4家教学医院和3家社区中心)进行单位成本计算。
计划剖宫产的估计平均成本显著低于计划阴道分娩(每位母婴7165美元对8,042美元;平均差值-877美元,95%可信区间-1286美元至-473美元)。初产妇计划剖宫产的估计平均成本低于计划阴道分娩(7255美元对8440美元),经产妇计划剖宫产的估计平均成本也低于计划阴道分娩(7071美元对7559美元)。尽管治疗效果在初产妇亚组中最大,但治疗与产次之间无统计学显著交互作用,因为产次等于零和产次等于一或更高时治疗效果差异的95%可信区间均包含零。
在足月臀位分娩试验中,对于足月单胎臀位分娩,计划剖宫产的成本低于计划阴道分娩。